Atlastin

spinqualitylabelsall models Structure of human atlastin cytoplasmic domain complex with GDP and AlF4 (PDB code 4ido). Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Atlastin (ATN) is a GTPase and a Golgi body transmembrane protein. ATN was shown to be required in membrane fusion and ER formation in Drosophila melanogaster. Disease Defects in the ATN gene are a cause of the degenerative spinal cord disorder spastic paraplegia type 3 and of hereditary sensory neuropathy type 1D. Structural highlights GDP/AlF4 binding site from human atlastin (PDB code 4ido). Water molecules shown as red spheres.

3D structures of atlastin

Updated on 07-January-2019

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• Atlastin-1
  • 4ido, 3q5e, 3qnu, 3qof – hATN cytoplasmic domain + GDP – human
    
  • 6b9d, 6b9e – hATN cytoplasmic domain (mutant) + GDP
    
  • 4idn – hATN cytoplasmic domain + GNP
    
  • 4idp – hATN cytoplasmic domain (mutant) + GNP
    
  • 4ido – hATN cytoplasmic domain + GDP + AlF4
    
  • 4idq, 6b9f – hATN cytoplasmic domain (mutant) + GDP + AlF4
    
  • 3x1d – ATN + GDP – Drosophila melanogaster
    
• Atlastin-3
  • 5vgr – hATN cytoplasmic domain + GDP
    

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