5tbv: Difference between revisions

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'''Unreleased structure'''


The entry 5tbv is ON HOLD  until Paper Publication
==Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase complexed with tubercidin==
<StructureSection load='5tbv' size='340' side='right'caption='[[5tbv]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[5tbv]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TBV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TBV FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TBN:2-(4-AMINO-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-3,4-DIOL'>TBN</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5cxq|5cxq]], [[5ko5|5ko5]], [[5ko6|5ko6]], [[5tbs|5tbs]], [[5tbt|5tbt]], [[5tbu|5tbu]]</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Purine-nucleoside_phosphorylase Purine-nucleoside phosphorylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.1 2.4.2.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tbv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tbv OCA], [http://pdbe.org/5tbv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tbv RCSB], [http://www.ebi.ac.uk/pdbsum/5tbv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tbv ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/A0A0U3AGT1_SCHMA A0A0U3AGT1_SCHMA]] The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.[PIRNR:PIRNR000477]


Authors: Faheem, M., Torini, J.R., Romanello, L., Brandao-Neto, J., Pereira, H.M.
==See Also==
 
*[[Purine nucleoside phosphorylase|Purine nucleoside phosphorylase]]
Description: Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase complexed with tubercidin
__TOC__
[[Category: Unreleased Structures]]
</StructureSection>
[[Category: Blood fluke]]
[[Category: Large Structures]]
[[Category: Purine-nucleoside phosphorylase]]
[[Category: Brandao-Neto, J]]
[[Category: Brandao-Neto, J]]
[[Category: Pereira, H.M]]
[[Category: Faheem, M]]
[[Category: Torini, J.R]]
[[Category: Pereira, H M]]
[[Category: Romanello, L]]
[[Category: Romanello, L]]
[[Category: Faheem, M]]
[[Category: Torini, J R]]
[[Category: Transferase]]

Revision as of 06:25, 17 April 2019

Crystal Structure of Isoform 2 of Purine Nucleoside Phosphorylase complexed with tubercidin

5tbv, resolution 1.95Å

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