4pdc: Difference between revisions

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==Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D==
==Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D==
<StructureSection load='4pdc' size='340' side='right' caption='[[4pdc]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
<StructureSection load='4pdc' size='340' side='right'caption='[[4pdc]], [[Resolution|resolution]] 1.99&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4pdc]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Cowpx Cowpx] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PDC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PDC FirstGlance]. <br>
<table><tr><td colspan='2'>[[4pdc]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Cowpx Cowpx] and [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4PDC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4PDC FirstGlance]. <br>
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== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN]] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.  
[[http://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN]] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.  
==See Also==
*[[NK cell receptor|NK cell receptor]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Cowpx]]
[[Category: Cowpx]]
[[Category: Human]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Structural genomic]]
[[Category: Structural genomic]]
[[Category: Fremont, D H]]
[[Category: Fremont, D H]]

Revision as of 07:11, 6 November 2019

Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D

4pdc, resolution 1.99Å

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