Adapter molecule crk: Difference between revisions

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== Function ==
== Function ==
      
      
'''Adapter molecule crk''' (Crk) ('''C'''T10 '''R'''egulatior of '''K'''inase) or '''p38''' is a proto-oncogene which participates in the Reelin signaling cascade.  Crk binds to several tyrosine-phosphorylated proteins.<ref>PMID:12086608</ref>   
'''Adapter molecule crk''' (Crk) ('''C'''T10 '''R'''egulatior of '''K'''inase) or '''p38''' is a proto-oncogene which participates in the Reelin signaling cascade.  Crk binds to several tyrosine-phosphorylated proteins.<ref>PMID:12086608</ref> See also [[SRC]] and [[Oncogenes & Tumor Suppressor Genes]].  


== Structural highlights ==
== Structural highlights ==

Latest revision as of 15:38, 20 January 2020

Structure of mouse Crk N terminal SH3 domain (magenta) complex with proline-rich peptide (green) (PDB entry 1cka)

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References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky