Cadherin 3D structures: Difference between revisions

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New page: == 3D Structures of Cadherin == Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| * CDH5 **2koh – mCDH5+PAR3-...
 
Michal Harel (talk | contribs)
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
*CDH1 encoded by CDH1
**[[6cxy]] – hCDH1 + antibody - human<br />


* CDH5  
* CDH5  
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* CDH23  
* CDH23  
 
**[[3mvs]], [[2whv]] – mCDH23 N-terminal<br />
**[[2kbr]] – hCDH23 peptide+harmonin – NMR <br />
**[[2kbr]] – hCDH23 peptide+harmonin – NMR - human<br />
**[[2kbs]] - hCDH23 C-terminal peptide+harmonin PDZ2 – NMR<br />
**[[2kbs]] - hCDH23 C-terminal peptide+harmonin PDZ2 – NMR<br />
**[[5wj8]] - hCDH23 EC13-EC14<br />
**[[5vvm]] - hCDH23 EC21-EC23<br />
**[[3mvs]], [[2whv]] – mCDH23 N-terminal<br />
**[[2wbx]] – mCDH23 EC1<br />
**[[2wbx]] – mCDH23 EC1<br />
**[[2wcp]] - mCDH23 EC2<br />
**[[2wcp]] - mCDH23 EC2<br />
**[[2wd0]] - mCDH23 EC1-EC2 (mutant)<br />
**[[2wd0]] - mCDH23 EC1-EC2 (mutant)<br />
**[[5w4t]] - CDH23 EC1-EC3 - zebrafish<br />
**[[5tfm]] - mCDH23 EC6-EC8<br />
**[[5tfm]] - mCDH23 EC6-EC8<br />
**[[5tfl]] - mCDH23 EC7-EC8<br />
**[[5tfl]] - mCDH23 EC7-EC8<br />
**[[5vh2]] - mCDH23 EC12-EC13 (mutant)<br />
**[[5vh2]] - mCDH23 EC12-EC13 (mutant)<br />
**[[5wj8]] - hCDH23 EC13-EC14<br />
**[[5wjm]] - mCDH23 EC17-EC18<br />
**[[5wjm]] - mCDH23 EC17-EC18<br />
**[[5tfk]] - mCDH23 EC19-EC21<br />
**[[5tfk]] - mCDH23 EC19-EC21<br />
**[[5i8d]], [[5ulu]], [[5un2]] - mCDH23 EC19-EC21 (mutant)<br />
**[[5i8d]], [[5ulu]], [[5un2]] - mCDH23 EC19-EC21 (mutant)<br />
**[[5vvm]] - hCDH23 EC21-EC23<br />
**[[5uz8]] - mCDH23 EC22-EC24<br />
**[[5uz8]] - mCDH23 EC22-EC24<br />
**[[5vt8]] - mCDH23 EC23-EC25<br />
**[[5vt8]] - mCDH23 EC23-EC25<br />
**[[4apx]], [[4aq8]], [[4axw]], [[4xxw]] - mCDH23 EC1-EC2 + Prot-CDH15<br />
**[[4apx]], [[4aq8]], [[4axw]], [[4xxw]] - mCDH23 EC1-EC2 + Prot-CDH15<br />
**[[4aqa]], [[4aqe]] - mCDH23 EC1-EC2 (mutant) + Prot-CDH15
**[[4aqa]], [[4aqe]] - mCDH23 EC1-EC2 (mutant) + Prot-CDH15<br />
**[[5w4t]] - CDH23 EC1-EC3 - zebrafish<br />


* C-CDH “classical”  
* C-CDH “classical”  
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* E-CDH epithelial or CDH1
* E-CDH epithelial or CDH1


**[[1q1p]], [[1ff5]], [[1edh]], [[3lne]], [[3lnf]], [[3lng]], [[3lnh]], [[3lni]], [[2qvf]] – mE-CDH EC1-EC2<br />
**[[3q2v]] – mE-CDH ectodomain<br />
**[[4zt1]], [[2o72]] – hE-CDH EC1-EC2<br />
**[[4zt1]], [[2o72]] – hE-CDH EC1-EC2<br />
**[[4zte]] – hE-CDH EC1-EC2 + inhibitor<br />
**[[4zte]] – hE-CDH EC1-EC2 + inhibitor<br />
**[[6fek]] – hE-CDH EC1-EC2 + antibody<br />
**[[6fek]] – hE-CDH EC1-EC2 + antibody<br />
**[[3ifq]] – hE-CDH EC1-EC3 <br />
**[[3ff7]], [[3ff8]] - hE-CDH EC1-EC3+NK cell receptor<br />
**[[2omt]], [[2omu]], [[2omx]], [[2omz]], [[2omv]], [[2omw]], [[2omy]] – hE-CDH EC1+internalin (mutant)<br />
**[[1q1p]], [[1ff5]], [[1edh]], [[3lne]], [[3lnf]], [[3lng]], [[3lnh]], [[3lni]], [[2qvf]] – mE-CDH EC1-EC2<br />
**[[3q2v]] – mE-CDH ectodomain<br />
**[[1edh]] - mE-CDH EC1-EC2+Ca<br />
**[[1edh]] - mE-CDH EC1-EC2+Ca<br />
**[[3q2l]], [[3q2n]], [[3qrb]] - mE-CDH EC1-EC2 (mutant)<br />
**[[3q2l]], [[3q2n]], [[3qrb]] - mE-CDH EC1-EC2 (mutant)<br />
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**[[1i7x]], [[1i7w]] – mE-CDH cytoplasmic domain +catenin<br />
**[[1i7x]], [[1i7w]] – mE-CDH cytoplasmic domain +catenin<br />
**[[4qd2]] – mE-CDH + botulinum neurotoxin<br />
**[[4qd2]] – mE-CDH + botulinum neurotoxin<br />
**[[3ifq]] – hE-CDH EC1-EC3 <br />
**[[3ff7]], [[3ff8]] - hE-CDH EC1-EC3+NK cell receptor<br />
**[[2omt]], [[2omu]], [[2omx]], [[2omz]], [[2omv]], [[2omw]], [[2omy]] – hE-CDH EC1+internalin (mutant)<br />
**[[1o6s]] – E-CDH N-terminal+internalin – ''Listeria monocytogenes''<br />
**[[1o6s]] – E-CDH N-terminal+internalin – ''Listeria monocytogenes''<br />
**[[4qd2]] – mE-CDH + botulinum neurotoxin<br />


*K-CDH kidney or CDH6
*K-CDH kidney or CDH6
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* T-CDH membrane bound  
* T-CDH membrane bound  


**[[2v37]] – hT-CDH N-terminal - NMR<br />
**[[3k5r]], [[6cg6]] – mT-CDH EC1-EC2<br />
**[[3k5r]], [[6cg6]] – mT-CDH EC1-EC2<br />
**[[3k6f]] - mT-CDH EC1<br />
**[[3k5s]] - cT-CDH EC1-EC2 <br />
**[[3k5s]] - cT-CDH EC1-EC2 <br />
**[[3k6i]] - cT-CDH EC1<br />
**[[3k6d]] - XlT-CDH EC1 <br />
**[[3k6d]] - XlT-CDH EC1 <br />
**[[3k6f]] - mT-CDH EC1<br />
**[[3k6i]] - cT-CDH EC1<br />
**[[2v37]] – hT-CDH N-terminal - NMR<br />


* N-CDH neuronal  
* N-CDH neuronal  
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*P-CDH placental or CDH3
*P-CDH placental or CDH3


**[[4nqq]] – mP-CDH EC1-EC2<br />
**[[4oy9]], [[4zml]], [[4zmn]], [[4zmq]], [[4zmt]], [[4zmw]], [[4zmz]] – hP-CDH EC1-EC2<br />
**[[4oy9]], [[4zml]], [[4zmn]], [[4zmq]], [[4zmt]], [[4zmw]], [[4zmz]] – hP-CDH EC1-EC2<br />
**[[4zmo]], [[4zmp]], [[4zmv]], [[4zmx]], [[4zmy]] – hP-CDH EC1-EC2 (mutant)<br />
**[[4zmo]], [[4zmp]], [[4zmv]], [[4zmx]], [[4zmy]] – hP-CDH EC1-EC2 (mutant)<br />
**[[5jyl]], [[5jym]] – hP-CDH EC1-EC2 + SCFV TSP7<br />
**[[5jyl]], [[5jym]] – hP-CDH EC1-EC2 + SCFV TSP7<br />
**[[4nqq]] – mP-CDH EC1-EC2<br />


*VE-CDH vascular epithelial
*VE-CDH vascular epithelial
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* Protocadherin  
* Protocadherin  


**[[6bx7]] - hProt-CDH1 EC1-EC4<br />
**[[6bx7]], [[6vfp]] - hProt-CDH1 EC1-EC4<br />
**[[2yst]] – hProt-CDH7 EC3 – NMR<br />
**[[2yst]] – hProt-CDH7 EC3 – NMR<br />
**[[6mga]] - hProt-CDH1 EC4<br />
**[[6pim]] - hProt-CDH1 EC3-EC4<br />
**[[6n2e]] - hProt-CDH15 EC1-EC2 + mCDH23<br />
**[[2ee0]] - hProt-CDH9 Ca domain – NMR<br />
**[[2ee0]] - hProt-CDH9 Ca domain – NMR<br />
**[[1wyj]] - mProt-CDH β 14 - NMR<br />
**[[1wyj]] - mProt-CDH β 14 - NMR<br />
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* Desmoglein  
* Desmoglein  


**[[2yqg]] – hDes-CDH2 EC1<br />
**[[2yqg]] – hDes-CDH2 EC1 47-162<br />
**[[5erd]] – hDes-CDH2 ectodomain<br />
**[[5erd]] – hDes-CDH2 ectodomain 50-602<br />
**[[5eqx]] – hDes-CDH3 ectodomain<br />
**[[5eqx]] – hDes-CDH3 ectodomain<br />
**[[6sit]] – hDes2 EC2-EC3 149-386 + adenovirus fiber protein <br />
**[[6qnt]], [[6qnu]] – hDesmc2 ectodomain + adenovirus fiber protein – Cryo EM<br />
**[[6qnt]], [[6qnu]] – hDesmc2 ectodomain + adenovirus fiber protein – Cryo EM<br />


Revision as of 06:14, 29 June 2020

3D Structures of Cadherin

Updated on 29-June-2020

    • 2kbr – hCDH23 peptide+harmonin – NMR
    • 2kbs - hCDH23 C-terminal peptide+harmonin PDZ2 – NMR
    • 5wj8 - hCDH23 EC13-EC14
    • 5vvm - hCDH23 EC21-EC23
    • 3mvs, 2whv – mCDH23 N-terminal
    • 2wbx – mCDH23 EC1
    • 2wcp - mCDH23 EC2
    • 2wd0 - mCDH23 EC1-EC2 (mutant)
    • 5tfm - mCDH23 EC6-EC8
    • 5tfl - mCDH23 EC7-EC8
    • 5vh2 - mCDH23 EC12-EC13 (mutant)
    • 5wjm - mCDH23 EC17-EC18
    • 5tfk - mCDH23 EC19-EC21
    • 5i8d, 5ulu, 5un2 - mCDH23 EC19-EC21 (mutant)
    • 5uz8 - mCDH23 EC22-EC24
    • 5vt8 - mCDH23 EC23-EC25
    • 4apx, 4aq8, 4axw, 4xxw - mCDH23 EC1-EC2 + Prot-CDH15
    • 4aqa, 4aqe - mCDH23 EC1-EC2 (mutant) + Prot-CDH15
    • 5w4t - CDH23 EC1-EC3 - zebrafish
  • C-CDH “classical”
    • 1l3w – XlC-CDH ectodomain - Xenopus laevis
    • 1q5b, 1q5c, 1q55, 1q5a – C-CDH model into desmosome – electron tomography
  • E-CDH epithelial or CDH1
  • K-CDH kidney or CDH6
    • 5veb – hK-CDH EC5 + antibody
    • 6cgu – mK-CDH EC1-EC2
  • T-CDH membrane bound
    • 2v37 – hT-CDH N-terminal - NMR
    • 3k5r, 6cg6 – mT-CDH EC1-EC2
    • 3k6f - mT-CDH EC1
    • 3k5s - cT-CDH EC1-EC2
    • 3k6i - cT-CDH EC1
    • 3k6d - XlT-CDH EC1
  • N-CDH neuronal
    • 1nch, 1nci – mN-CDH
    • 1ncg – mN-CDH (mutant)
    • 2qvi, 4nuq – mN-CDH EC1-EC2
    • 4num, 4nup – mN-CDH EC1-EC2 (mutant)
    • 1ncj – mN-CDH two domains
    • 3q2w – mN-CDH ectodomain
    • 1op4 - mN-CDH prodomain - NMR
    • 3ubf – DmN-CDH ectodomain – Drosophila melanogaster
    • 3ubh - DmN-CDH EC1-EC4
    • 3ubg - DmN-CDH EC1-EC3
  • P-CDH placental or CDH3
  • VE-CDH vascular epithelial
    • 3ppe – cVE-CDH EC1+EC2
  • Protocadherin
    • 6bx7, 6vfp - hProt-CDH1 EC1-EC4
    • 2yst – hProt-CDH7 EC3 – NMR
    • 6mga - hProt-CDH1 EC4
    • 6pim - hProt-CDH1 EC3-EC4
    • 6n2e - hProt-CDH15 EC1-EC2 + mCDH23
    • 2ee0 - hProt-CDH9 Ca domain – NMR
    • 1wyj - mProt-CDH β 14 - NMR
    • 1wuz - mProt-CDH4 EC1 – NMR
    • 5cyx - mProt-CDH2 EC1+EC2+EC3
    • 5szl - mProt-CDH γ A1 EC1-EC4
  • Desmoglein
    • 2yqg – hDes-CDH2 EC1 47-162
    • 5erd – hDes-CDH2 ectodomain 50-602
    • 5eqx – hDes-CDH3 ectodomain
    • 6sit – hDes2 EC2-EC3 149-386 + adenovirus fiber protein
    • 6qnt, 6qnu – hDesmc2 ectodomain + adenovirus fiber protein – Cryo EM
  • Desmocollin
    • 5iry – hDesmc1 ectodomain
    • 5erp, 5j5j – hDesmc2 ectodomain

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Openfox

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