2wo8: Difference between revisions
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==MMP12 complex with a beta hydroxy carboxylic acid== | ==MMP12 complex with a beta hydroxy carboxylic acid== | ||
<StructureSection load='2wo8' size='340' side='right' caption='[[2wo8]], [[Resolution|resolution]] 2.00Å' scene=''> | <StructureSection load='2wo8' size='340' side='right'caption='[[2wo8]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[2wo8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WO8 OCA]. For a <b>guided tour on the structure components</b> use [http:// | <table><tr><td colspan='2'>[[2wo8]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WO8 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2WO8 FirstGlance]. <br> | ||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=023:N^2^-[(2R)-2-{(1S)-1-[FORMYL(HYDROXY)AMINO]ETHYL}-5-PHENYLPENTANOYL]-N,3-DIMETHYL-L-VALINAMIDE'>023</scene>, <scene name='pdbligand=077:(3S)-5-BIPHENYL-4-YL-3-HYDROXYPENTANOIC+ACID'>077</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=023:N^2^-[(2R)-2-{(1S)-1-[FORMYL(HYDROXY)AMINO]ETHYL}-5-PHENYLPENTANOYL]-N,3-DIMETHYL-L-VALINAMIDE'>023</scene>, <scene name='pdbligand=077:(3S)-5-BIPHENYL-4-YL-3-HYDROXYPENTANOIC+ACID'>077</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ycm|1ycm]], [[2woa|2woa]], [[1os9|1os9]], [[1utt|1utt]], [[1y93|1y93]], [[1z3j|1z3j]], [[2w0d|2w0d]], [[1os2|1os2]], [[2wo9|2wo9]], [[1jk3|1jk3]], [[1ros|1ros]], [[1utz|1utz]], [[1rmz|1rmz]], [[1jiz|1jiz]]</td></tr> | <tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ycm|1ycm]], [[2woa|2woa]], [[1os9|1os9]], [[1utt|1utt]], [[1y93|1y93]], [[1z3j|1z3j]], [[2w0d|2w0d]], [[1os2|1os2]], [[2wo9|2wo9]], [[1jk3|1jk3]], [[1ros|1ros]], [[1utz|1utz]], [[1rmz|1rmz]], [[1jiz|1jiz]]</td></tr> | ||
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] </span></td></tr> | <tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Macrophage_elastase Macrophage elastase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.65 3.4.24.65] </span></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http:// | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2wo8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wo8 OCA], [http://pdbe.org/2wo8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2wo8 RCSB], [http://www.ebi.ac.uk/pdbsum/2wo8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2wo8 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
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==See Also== | ==See Also== | ||
*[[Matrix metalloproteinase|Matrix metalloproteinase]] | *[[Matrix metalloproteinase 3D structures|Matrix metalloproteinase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Macrophage elastase]] | [[Category: Macrophage elastase]] | ||
[[Category: Amour, A J]] | [[Category: Amour, A J]] | ||
Revision as of 08:58, 1 July 2020
MMP12 complex with a beta hydroxy carboxylic acid
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Human
- Large Structures
- Macrophage elastase
- Amour, A J
- Baddeley, S J
- Brown, D
- Convery, M A
- Egan, D
- Gaines, S
- Gross, J W
- Herbert, S
- Holmes, I P
- Lorthioir, O
- Martin, S L
- Singh, O M.P
- Smith, R H
- Strelow, J M
- Walker, A
- Watson, S P
- Extracellular matrix
- Glycoprotein
- Hydrolase
- Matrix metalloprotease mmp-12 complex structure
- Metal-binding
- Metalloprotease
- Polymorphism
- Protease
- Secreted
- Zymogen
