Sandbox Reserved 1660: Difference between revisions
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== Impact of ligand-binding == | == Impact of ligand-binding == | ||
<ref>{{Information, N. C. for B.; Pike, U. S. N. L. of M. R.; BethesdaMD; 20894USA. 3GMQ: Structure of mouse CD1d expressed in SF9 cells, no ligand added https://www.ncbi.nlm.nih.gov/Structure/pdb/3GMQ (accessed Dec 5, 2020).}}</ref> | |||
== Appications == | == Appications == | ||
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== References == | == References == | ||
{{Reflist}} | |||
This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | This is a sample scene created with SAT to <scene name="/12/3456/Sample/1">color</scene> by Group, and another to make <scene name="/12/3456/Sample/2">a transparent representation</scene> of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes. | ||
Revision as of 14:06, 10 January 2021
| This Sandbox is Reserved from 26/11/2020, through 26/11/2021 for use in the course "Structural Biology" taught by Bruno Kieffer at the University of Strasbourg, ESBS. This reservation includes Sandbox Reserved 1643 through Sandbox Reserved 1664. |
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Structure of mouse CD1d expressed in SF9 cells, no ligand added
CD1 (Cluster of Differentiation 1) is a family of glycoproteins involved in the presentation of antigens on the surface of specific cells to NKT cells. Amongst these CD1-presenting cells can be counted splenic dendritic cells, marginal zone B cells and CD4+CD8+ thymocytes. This family is made of two main groups: group 1 is composed of CD1a, b and c proteins and group 2 is composed of CD1d proteins.
Thus, the structure and function of such proteins in mice are akin to those of humans. Mice doesn’t express group 1 CD1 molecules. Instead, they have two kinds of CD1d molecules. Therefore, they have been widely used to characterize the functions of CD1d and CD1d-dependent NKT cells in many diseases.
Function
Structure
Impact of ligand-binding
Appications
See Also
References
This is a sample scene created with SAT to color by Group, and another to make a transparent representation of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.
</StructureSection>