Corticosteroids

spinqualitylabelsall models FMN containing pentaerythritol tetranitrate reductase complex with prednisone (PDB entry 1h61) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes. Prednisone and its derivatives have some mineralocorticoid action in addition to the glucocorticoid effect. Dexamethasone is a glucocorticoid medication. It is the most potent glucocorticoid and it has not mineralocorticoid potency. Human glucocorticoid receptor ligand-binding domain bound to dexamethasone (1m2z). Glucocorticoids Mineralocorticoids Pentaerythritol tetranitrate reductase active site contains the cofactor FMN and the substrate steroid prednisone. Water molecules are shown as red spheres. Whole active site. Corticosteroid-binding globulin Cortisol (hydrocortisone) is a corticosteroid with both glucocorticoid and mineralocorticoid activity and effects.

See also:

• glucocorticoids

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Alexander Berchansky