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==crystal structure of putative mandelate racemase / muconate lactonizing enzyme from Vibrionales bacterium SWAT-3==
==crystal structure of putative mandelate racemase / muconate lactonizing enzyme from Vibrionales bacterium SWAT-3==
<StructureSection load='3dfh' size='340' side='right' caption='[[3dfh]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='3dfh' size='340' side='right'caption='[[3dfh]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3dfh]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibbs Vibbs]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3DFH FirstGlance]. <br>
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3DFH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3DFH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3dfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dfh OCA], [https://pdbe.org/3dfh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3dfh RCSB], [https://www.ebi.ac.uk/pdbsum/3dfh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3dfh ProSAT], [https://www.topsan.org/Proteins/NYSGXRC/3dfh TOPSAN]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VSWAT3_13707 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=391574 VIBBS])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3dfh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3dfh OCA], [http://pdbe.org/3dfh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=3dfh RCSB], [http://www.ebi.ac.uk/pdbsum/3dfh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=3dfh ProSAT], [http://www.topsan.org/Proteins/NYSGXRC/3dfh TOPSAN]</span></td></tr>
</table>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/IMAND_VIBBS IMAND_VIBBS]] Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.<ref>PMID:24697546</ref> 
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Mandelate racemase|Mandelate racemase]]
*[[Mandelate racemase|Mandelate racemase]]
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Vibbs]]
[[Category: Large Structures]]
[[Category: Almo, S C]]
[[Category: Almo SC]]
[[Category: Burley, S K]]
[[Category: Burley SK]]
[[Category: Malashkevich, V N]]
[[Category: Malashkevich VN]]
[[Category: Meyer, A J]]
[[Category: Meyer AJ]]
[[Category: Structural genomic]]
[[Category: Sauder JM]]
[[Category: Sauder, J M]]
[[Category: Toro R]]
[[Category: Toro, R]]
[[Category: Wasserman SR]]
[[Category: Wasserman, S R]]
[[Category: Isomerase]]
[[Category: NYSGXRC, New York SGX Research Center for Structural Genomics]]
[[Category: PSI, Protein structure initiative]]
[[Category: Putative mandelate racemase / muconate lactonizing enzyme]]

Revision as of 07:57, 9 February 2022

crystal structure of putative mandelate racemase / muconate lactonizing enzyme from Vibrionales bacterium SWAT-3

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