3q90: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 1: | Line 1: | ||
==Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1== | ==Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1== | ||
<StructureSection load='3q90' size='340' side='right' caption='[[3q90]], [[Resolution|resolution]] 1.70Å' scene=''> | <StructureSection load='3q90' size='340' side='right'caption='[[3q90]], [[Resolution|resolution]] 1.70Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[3q90]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[3q90]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3Q90 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3Q90 FirstGlance]. <br> | ||
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3q91|3q91]], [[3q93|3q93]]</td></tr> | </td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3q91|3q91]], [[3q93|3q93]]</div></td></tr> | ||
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">G3BP, G3BP1 ([ | <tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">G3BP, G3BP1 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3q90 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3q90 OCA], [https://pdbe.org/3q90 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3q90 RCSB], [https://www.ebi.ac.uk/pdbsum/3q90 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3q90 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
[[ | [[https://www.uniprot.org/uniprot/G3BP1_HUMAN G3BP1_HUMAN]] May be a regulated effector of stress granule assembly. Phosphorylation-dependent sequence-specific endoribonuclease in vitro. Cleaves exclusively between cytosine and adenine and cleaves MYC mRNA preferentially at the 3'-UTR. ATP- and magnesium-dependent helicase. Unwinds preferentially partial DNA and RNA duplexes having a 17 bp annealed portion and either a hanging 3' tail or hanging tails at both 5'- and 3'-ends. Unwinds DNA/DNA, RNA/DNA, and RNA/RNA substrates with comparable efficiency. Acts unidirectionally by moving in the 5' to 3' direction along the bound single-stranded DNA.<ref>PMID:9889278</ref> <ref>PMID:11604510</ref> | ||
== References == | == References == | ||
<references/> | <references/> | ||
| Line 15: | Line 15: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Human]] | [[Category: Human]] | ||
[[Category: Large Structures]] | |||
[[Category: Arrowsmith, C H]] | [[Category: Arrowsmith, C H]] | ||
[[Category: Berg, S Van Der]] | [[Category: Berg, S Van Der]] | ||
Revision as of 05:58, 8 June 2022
Crystal structure of the NTF2 domain of Ras GTPase-activating protein-binding protein 1
| ||||||||||||
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Human
- Large Structures
- Arrowsmith, C H
- Berg, S Van Der
- Berglund, H
- Bountra, C
- Collins, R
- Edwards, A M
- Ekblad, T
- Flodin, S
- Flores, A
- Graslund, S
- Hammarstrom, M
- Johansson, I
- Karlberg, T
- Kol, S
- Kotenyova, T
- Kouznetsova, E
- Moche, M
- Nordlund, P
- Nyman, T
- Persson, C
- Structural genomic
- Schuler, H
- Schutz, P
- Siponen, M I
- Thorsell, A G
- Tresaugues, L
- Wahlberg, E
- Weigelt, J
- Welin, M
- Dna and rna binding
- Hydrolase
- Nucleus
- Plasma membrane
- Protein binding and helicase
- Sgc
