7fi7: Difference between revisions

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====

==Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D==

== Structural highlights ==

<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>

<table><tr><td colspan='2'>[[7fi7]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FI7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FI7 FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fi7 OCA], [https://pdbe.org/7fi7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fi7 RCSB], [https://www.ebi.ac.uk/pdbsum/7fi7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fi7 ProSAT]</span></td></tr>

</table>

== Function ==

[[https://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN]] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: Large Structures]]

[[Category: ~~Z-disk~~]]

[[Category: Cai W]]

[[Category: Li Y]]

[[Category: Liu J]]

[[Category: Peng S]]

[[Category: Tian Y]]

[[Category: Xu T]]

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-====
+==Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D==
-<StructureSection load='7fi7' size='340' side='right'caption='[[7fi7]]' scene=''>
+<StructureSection load='7fi7' size='340' side='right'caption='[[7fi7]], [[Resolution|resolution]] 2.78&Aring;' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br>
+<table><tr><td colspan='2'>[[7fi7]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FI7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FI7 FirstGlance]. <br>
 </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fi7 OCA], [https://pdbe.org/7fi7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fi7 RCSB], [https://www.ebi.ac.uk/pdbsum/7fi7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fi7 ProSAT]</span></td></tr>
 </table>
+== Function ==
+[[https://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN]] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.
 __TOC__
 </StructureSection>
+[[Category: Homo sapiens]]
 [[Category: Large Structures]]
-[[Category: Z-disk]]
+[[Category: Cai W]]
+[[Category: Li Y]]
+[[Category: Liu J]]
+[[Category: Peng S]]
+[[Category: Tian Y]]
+[[Category: Xu T]]