7fi7
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Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
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Structural highlights
FunctionNKG2D_HUMAN Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. See AlsoContents | ||||||||||||||||||
This page was last modified 17:16, 29 November 2023.