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==W116L-OYE1 complexed with (R)-carvone==
==W116L-OYE1 complexed with (R)-carvone==
<StructureSection load='4gwe' size='340' side='right' caption='[[4gwe]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
<StructureSection load='4gwe' size='340' side='right'caption='[[4gwe]], [[Resolution|resolution]] 1.45&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4gwe]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lager_yeast Lager yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWE OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4GWE FirstGlance]. <br>
<table><tr><td colspan='2'>[[4gwe]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharomyces_pastorianus Saccharomyces pastorianus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GWE OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GWE FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=07V:(5R)-2-METHYL-5-(PROP-1-EN-2-YL)CYCLOHEX-2-EN-1-ONE'>07V</scene>, <scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=07V:(5R)-2-METHYL-5-(PROP-1-EN-2-YL)CYCLOHEX-2-EN-1-ONE'>07V</scene>, <scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FMN:FLAVIN+MONONUCLEOTIDE'>FMN</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4gbu|4gbu]], [[4ge8|4ge8]], [[3txz|3txz]], [[4gxm|4gxm]], [[3rnd|3rnd]], [[3tx9|3tx9]], [[4h4i|4h4i]], [[4h6k|4h6k]], [[4k7v|4k7v]], [[4k7y|4k7y]], [[4k8e|4k8e]], [[4k8h|4k8h]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gwe OCA], [https://pdbe.org/4gwe PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gwe RCSB], [https://www.ebi.ac.uk/pdbsum/4gwe PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gwe ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">OYE1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=27292 Lager yeast])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/NADPH_dehydrogenase NADPH dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.6.99.1 1.6.99.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4gwe FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gwe OCA], [http://pdbe.org/4gwe PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4gwe RCSB], [http://www.ebi.ac.uk/pdbsum/4gwe PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4gwe ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/OYE1_SACPS OYE1_SACPS]] Oxidizes beta-NADH, beta-NADPH, and alpha-NADPH.  
[https://www.uniprot.org/uniprot/OYE1_SACPS OYE1_SACPS] Oxidizes beta-NADH, beta-NADPH, and alpha-NADPH.


==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Lager yeast]]
[[Category: Large Structures]]
[[Category: NADPH dehydrogenase]]
[[Category: Saccharomyces pastorianus]]
[[Category: Pompeu, Y A]]
[[Category: Pompeu YA]]
[[Category: Stewart, J D]]
[[Category: Stewart JD]]
[[Category: Alpha/beta barrel]]
[[Category: Atomic resolution]]
[[Category: Biocatalysis]]
[[Category: Carvone]]
[[Category: Enantioselectivity]]
[[Category: Enoate reductase]]
[[Category: Flipped binding]]
[[Category: Old Yellow Enzyme]]
[[Category: Oxidoreductase]]
[[Category: Oye]]
[[Category: Reductase]]
[[Category: Tim barrel]]

Revision as of 07:22, 26 October 2022

W116L-OYE1 complexed with (R)-carvone

4gwe, resolution 1.45Å

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