4hkr: Difference between revisions

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==Calcium release-activated calcium (CRAC) channel ORAI==
==Calcium release-activated calcium (CRAC) channel ORAI==
<StructureSection load='4hkr' size='340' side='right' caption='[[4hkr]], [[Resolution|resolution]] 3.35&Aring;' scene=''>
<StructureSection load='4hkr' size='340' side='right'caption='[[4hkr]], [[Resolution|resolution]] 3.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4hkr]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HKR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HKR FirstGlance]. <br>
<table><tr><td colspan='2'>[[4hkr]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HKR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HKR FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BA:BARIUM+ION'>BA</scene>, <scene name='pdbligand=FE:FE+(III)+ION'>FE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">olf186-F, CRACM1, olf186, CG11430 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hkr OCA], [https://pdbe.org/4hkr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hkr RCSB], [https://www.ebi.ac.uk/pdbsum/4hkr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hkr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hkr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hkr OCA], [http://pdbe.org/4hkr PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hkr RCSB], [http://www.ebi.ac.uk/pdbsum/4hkr PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hkr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CRCM1_DROME CRCM1_DROME]] Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores. Regulates transcription factor NFAT nuclear import.<ref>PMID:16582901</ref> <ref>PMID:16645049</ref>
[https://www.uniprot.org/uniprot/CRCM1_DROME CRCM1_DROME] Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores. Regulates transcription factor NFAT nuclear import.<ref>PMID:16582901</ref> <ref>PMID:16645049</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Drome]]
[[Category: Drosophila melanogaster]]
[[Category: Hou, X]]
[[Category: Large Structures]]
[[Category: Long, S B]]
[[Category: Hou X]]
[[Category: Calcium channel]]
[[Category: Long SB]]
[[Category: Eukaryotic membrane protein]]
[[Category: Ion channel]]
[[Category: Membrane]]
[[Category: Membrane protein]]
[[Category: Orai1]]
[[Category: Stim]]
[[Category: Transport protein]]