Cadherin 3D structures: Difference between revisions

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Michal Harel (talk | contribs)
32,831 edits
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Line 32: Line 32:
*CDH encoded by CDH17
*CDH encoded by CDH17


**[[6ulm]] – hCDH17 EC1-EC2<br />
**[[6ulm]], [[7ev1]] – hCDH17 EC1-EC2<br />
**[[7cym]] – hCDH17 EC1-EC4<br />


* CDH20  
* CDH20  
Line 55: Line 56:
**[[5tfl]] - mCDH23 EC7-EC8<br />
**[[5tfl]] - mCDH23 EC7-EC8<br />
**[[5vh2]] - mCDH23 EC12-EC13 (mutant)<br />
**[[5vh2]] - mCDH23 EC12-EC13 (mutant)<br />
**[[7skh]] - mCDH23 EC16-EC17<br />
**[[5wjm]] - mCDH23 EC17-EC18<br />
**[[5wjm]] - mCDH23 EC17-EC18<br />
**[[5tfk]] - mCDH23 EC19-EC21<br />
**[[5tfk]] - mCDH23 EC19-EC21<br />
Line 62: Line 64:
**[[4apx]], [[4aq8]], [[4axw]], [[4xxw]] - mCDH23 EC1-EC2 + Prot-CDH15<br />
**[[4apx]], [[4aq8]], [[4axw]], [[4xxw]] - mCDH23 EC1-EC2 + Prot-CDH15<br />
**[[4aqa]], [[4aqe]] - mCDH23 EC1-EC2 (mutant) + Prot-CDH15<br />
**[[4aqa]], [[4aqe]] - mCDH23 EC1-EC2 (mutant) + Prot-CDH15<br />
**[[7n4p]] – CDH23 EC1-EC2 - lizard<br />
**[[7sgx]] – CDH23 EC1-EC2 - turtle<br />
**[[7sb6]], [[7scm]] – CDH23 EC1-EC2 - synthetic<br />
**[[5w4t]] - CDH23 EC1-EC3 - zebrafish<br />
**[[5w4t]] - CDH23 EC1-EC3 - zebrafish<br />


Line 68: Line 73:
**[[1l3w]] – XlC-CDH ectodomain - ''Xenopus laevis''<br />
**[[1l3w]] – XlC-CDH ectodomain - ''Xenopus laevis''<br />
**[[1q5b]], [[1q5c]], [[1q55]], [[1q5a]] – C-CDH model into desmosome – electron tomography<br />
**[[1q5b]], [[1q5c]], [[1q55]], [[1q5a]] – C-CDH model into desmosome – electron tomography<br />
**[[7tni]] - CDH23 EC12 (mutant) – tobacco moth<br />


* E-CDH epithelial or CDH1
* E-CDH epithelial or CDH1
Line 74: Line 80:
**[[4zte]] – hE-CDH EC1-EC2 + inhibitor<br />
**[[4zte]] – hE-CDH EC1-EC2 + inhibitor<br />
**[[6fek]], [[6vel]] – hE-CDH EC1-EC2 + antibody<br />
**[[6fek]], [[6vel]] – hE-CDH EC1-EC2 + antibody<br />
**[[7stz]] – hE-CDH EC1-EC5 + antibody<br />
**[[3ifq]] – hE-CDH EC1-EC3 <br />
**[[3ifq]] – hE-CDH EC1-EC3 <br />
**[[3ff7]], [[3ff8]] - hE-CDH EC1-EC3+NK cell receptor<br />
**[[3ff7]], [[3ff8]] - hE-CDH EC1-EC3+NK cell receptor<br />
Line 115: Line 122:
*P-CDH placental or CDH3
*P-CDH placental or CDH3


**[[4oy9]], [[4zml]], [[4zmn]], [[4zmq]], [[4zmt]], [[4zmw]], [[4zmz]], [[6ztb]] – hP-CDH EC1-EC2<br />
**[[4oy9]], [[4zml]], [[4zmn]], [[4zmq]], [[4zmt]], [[4zmw]], [[4zmz]], [[6ztb]] – hP-CDH EC1-EC2 residues 108-324<br />
**[[4zmo]], [[4zmp]], [[4zmv]], [[4zmx]], [[4zmy]] – hP-CDH EC1-EC2 (mutant)<br />
**[[4zmo]], [[4zmp]], [[4zmv]], [[4zmx]], [[4zmy]] – hP-CDH EC1-EC2 (mutant)<br />
**[[5jyl]], [[5jym]] – hP-CDH EC1-EC2 + SCFV TSP7<br />
**[[5jyl]], [[5jym]] – hP-CDH EC1-EC2 + SCFV TSP7<br />
**[[6ztr]] – hP-CDH EC1-EC2 + antibody<br />
**[[6ztr]] – hP-CDH EC1-EC2 + antibody<br />
**[[7cme]], [[7cmf]] – hP-CDH EC1-EC2 + inhibitor<br />
**[[4nqq]] – mP-CDH EC1-EC2<br />
**[[4nqq]] – mP-CDH EC1-EC2<br />


Line 143: Line 151:
**[[6vfr]] - hProt-CDH18 EC1-EC4 <br />
**[[6vfr]] - hProt-CDH18 EC1-EC4 <br />
**[[6vfu]] - hProt-CDH19 EC1-EC4 <br />
**[[6vfu]] - hProt-CDH19 EC1-EC4 <br />
**[[7n86]] - hProt-CDH24 EC1-EC2 <br />
**[[6meq]], [[6mer]] - hProt-CDH1 g B3 EC1-EC4  <br />
**[[6meq]], [[6mer]] - hProt-CDH1 g B3 EC1-EC4  <br />
**[[6c13]] - mProt-CDH15 – Cryo EM<br />
**[[6c13]] - mProt-CDH15 – Cryo EM<br />
Line 157: Line 166:
**[[6e6b]] - mProt-CDH γ B4 EC domain<br />
**[[6e6b]] - mProt-CDH γ B4 EC domain<br />
**[[5v5x]] - mProt-CDH γ B7 EC3-EC6<br />
**[[5v5x]] - mProt-CDH γ B7 EC3-EC6<br />
**[[7jgz]], [[7rgf]] - mProt-CDH gamma C4 EC1-EC4<br />
**[[6vg1]] - Prot-CDH 8.1 EC1-EC6 - frog<br />
**[[6vg1]] - Prot-CDH 8.1 EC1-EC6 - frog<br />
**[[6pgw]] - zProt-CDH19 EC3-EC6 <br />
**[[6pgw]] - zProt-CDH19 EC3-EC6 <br />

Revision as of 08:12, 9 November 2022

3D Structures of Cadherin

Updated on 09-November-2022

    • 2kbr – hCDH23 peptide+harmonin – NMR
    • 2kbs - hCDH23 C-terminal peptide+harmonin PDZ2 – NMR
    • 5wj8 - hCDH23 EC13-EC14
    • 5vvm - hCDH23 EC21-EC23
    • 3mvs, 2whv – mCDH23 N-terminal
    • 2wbx – mCDH23 EC1
    • 2wcp - mCDH23 EC2
    • 2wd0 - mCDH23 EC1-EC2 (mutant)
    • 5tfm - mCDH23 EC6-EC8
    • 5tfl - mCDH23 EC7-EC8
    • 5vh2 - mCDH23 EC12-EC13 (mutant)
    • 7skh - mCDH23 EC16-EC17
    • 5wjm - mCDH23 EC17-EC18
    • 5tfk - mCDH23 EC19-EC21
    • 5i8d, 5ulu, 5un2 - mCDH23 EC19-EC21 (mutant)
    • 5uz8 - mCDH23 EC22-EC24
    • 5vt8 - mCDH23 EC23-EC25
    • 4apx, 4aq8, 4axw, 4xxw - mCDH23 EC1-EC2 + Prot-CDH15
    • 4aqa, 4aqe - mCDH23 EC1-EC2 (mutant) + Prot-CDH15
    • 7n4p – CDH23 EC1-EC2 - lizard
    • 7sgx – CDH23 EC1-EC2 - turtle
    • 7sb6, 7scm – CDH23 EC1-EC2 - synthetic
    • 5w4t - CDH23 EC1-EC3 - zebrafish
  • C-CDH “classical”
    • 1l3w – XlC-CDH ectodomain - Xenopus laevis
    • 1q5b, 1q5c, 1q55, 1q5a – C-CDH model into desmosome – electron tomography
    • 7tni - CDH23 EC12 (mutant) – tobacco moth
  • E-CDH epithelial or CDH1
  • K-CDH kidney or CDH6
    • 5veb – hK-CDH EC5 + antibody
    • 6cgu – mK-CDH EC1-EC2
  • T-CDH membrane bound
    • 2v37 – hT-CDH N-terminal - NMR
    • 3k5r, 6cg6 – mT-CDH EC1-EC2
    • 3k6f - mT-CDH EC1
    • 3k5s - cT-CDH EC1-EC2
    • 3k6i - cT-CDH EC1
    • 3k6d - XlT-CDH EC1
  • N-CDH neuronal
    • 1nch, 1nci – mN-CDH
    • 1ncg – mN-CDH (mutant)
    • 2qvi, 4nuq – mN-CDH EC1-EC2
    • 4num, 4nup – mN-CDH EC1-EC2 (mutant)
    • 1ncj – mN-CDH two domains
    • 3q2w – mN-CDH ectodomain
    • 1op4 - mN-CDH prodomain - NMR
    • 3ubf – DmN-CDH ectodomain – Drosophila melanogaster
    • 3ubh - DmN-CDH EC1-EC4
    • 3ubg - DmN-CDH EC1-EC3
  • P-CDH placental or CDH3
  • VE-CDH vascular epithelial
    • 3ppe – cVE-CDH EC1+EC2
  • Protocadherin
    • 6bx7, 6mga, 6vfp - hProt-CDH1 EC1-EC4
    • 2yst – hProt-CDH7 EC3 – NMR
    • 6pim - hProt-CDH1 EC3-EC4
    • 6vfv - hProt-CDH8 EC5-EC6
    • 2ee0 - hProt-CDH9 Ca domain – NMR
    • 6vfq, 6vfw - hProt-CDH10 EC1-EC4
    • 6vg4 - hProt-CDH10 ectodomain
    • 6n22 - hProt-CDH15 EC1-EC2
    • 6n2e - hProt-CDH15 EC1-EC2 + mCDH23
    • 6mfo - hProt-CDH15 EC1-EC3 (mutant)
    • 6eb5 - hProt-CDH15 EC2-EC3 (mutant)
    • 6e8f - hProt-CDH15 EC3-EC5
    • 5t4n - hProt-CDH15 EC3-EC5 (mutant)
    • 6vft - hProt-CDH17 EC1-EC4
    • 6vfr - hProt-CDH18 EC1-EC4
    • 6vfu - hProt-CDH19 EC1-EC4
    • 7n86 - hProt-CDH24 EC1-EC2
    • 6meq, 6mer - hProt-CDH1 g B3 EC1-EC4
    • 6c13 - mProt-CDH15 – Cryo EM
    • 1wyj - mProt-CDH β 14 - NMR
    • 1wuz - mProt-CDH4 EC1 – NMR
    • 5cyx, 6cv7 - mProt-CDH2 EC1+EC2+EC3
    • 6bxu - mProt-CDH15 EC5-EC7 (mutant)
    • 6bwn - mProt-CDH15 EC6-EC7
    • 5tpk - mProt-CDH15 EC7-EC8 (mutant)
    • 6c10 - mProt-CDH15 EC11
    • 6eet - mProt-CDH2 EC9
    • 5szl - mProt-CDH γ A1 EC1-EC4
    • 5t9t - mProt-CDH γ B2 EC1-EC5
    • 6e6b - mProt-CDH γ B4 EC domain
    • 5v5x - mProt-CDH γ B7 EC3-EC6
    • 7jgz, 7rgf - mProt-CDH gamma C4 EC1-EC4
    • 6vg1 - Prot-CDH 8.1 EC1-EC6 - frog
    • 6pgw - zProt-CDH19 EC3-EC6
  • Desmoglein
    • 2yqg – hDes-2 EC1 47-162
    • 5erd – hDes-2 ectodomain 50-602
    • 5eqx – hDes-3 ectodomain
    • 6sit – hDes2 EC2-EC3 149-386 + adenovirus fiber protein
    • 6qnt, 6qnu, 7agf, 7agg – hDesmc2 ectodomain + adenovirus fiber protein – Cryo EM
    • 7a7d – hDes-2 + desmocollin-2 – Cryo EM
  • Desmocollin
    • 5iry – hDesmc1 ectodomain
    • 5erp – hDesmc2 EC2-EC5
    • 5j5j – hDesmc2 EC1 + Des-2 EC2-EC5

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Openfox

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