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<StructureSection load='5bzo' size='340' side='right'caption='[[5bzo]], [[Resolution|resolution]] 1.22&Aring;' scene=''>
<StructureSection load='5bzo' size='340' side='right'caption='[[5bzo]], [[Resolution|resolution]] 1.22&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5bzo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5BZO FirstGlance]. <br>
<table><tr><td colspan='2'>[[5bzo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5BZO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5BZO FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4XC:3-(8-AMINO-3,4-DIHYDROISOQUINOLIN-2(1H)-YL)-N-METHYLPROPANAMIDE'>4XC</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4XC:3-(8-AMINO-3,4-DIHYDROISOQUINOLIN-2(1H)-YL)-N-METHYLPROPANAMIDE'>4XC</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5bzc|5bzc]], [[5bze|5bze]], [[5bzf|5bzf]], [[5bzg|5bzg]], [[5bzh|5bzh]], [[5bzi|5bzi]], [[5bzj|5bzj]], [[5bzm|5bzm]], [[5bzn|5bzn]], [[5bzq|5bzq]], [[5bzp|5bzp]], [[5bzr|5bzr]], [[5bzs|5bzs]], [[5bzt|5bzt]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5bzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bzo OCA], [https://pdbe.org/5bzo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5bzo RCSB], [https://www.ebi.ac.uk/pdbsum/5bzo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5bzo ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cd44, Ly-24 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5bzo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5bzo OCA], [http://pdbe.org/5bzo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5bzo RCSB], [http://www.ebi.ac.uk/pdbsum/5bzo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5bzo ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE]] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.  
[https://www.uniprot.org/uniprot/CD44_MOUSE CD44_MOUSE] Main cell surface receptor for hyaluronate. Adhesion to mucosal high endothelial venule and to types I and VI collagen. Probably involved in matrix adhesion, lymphocyte activation and lymph node homing.


==See Also==
==See Also==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lk3 transgenic mice]]
[[Category: Mus musculus]]
[[Category: Finzel, B C]]
[[Category: Finzel BC]]
[[Category: Liu, L K]]
[[Category: Liu LK]]
[[Category: Link module]]
[[Category: Protein binding]]

Revision as of 06:13, 7 June 2023

Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule

5bzo, resolution 1.22Å

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