7q2u: Difference between revisions
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==The crystal structure of the HINT1 Q62A mutant.== | ==The crystal structure of the HINT1 Q62A mutant.== | ||
<StructureSection load='7q2u' size='340' side='right'caption='[[7q2u]]' scene=''> | <StructureSection load='7q2u' size='340' side='right'caption='[[7q2u]], [[Resolution|resolution]] 2.27Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Q2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Q2U FirstGlance]. <br> | <table><tr><td colspan='2'>[[7q2u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Q2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Q2U FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q2u OCA], [https://pdbe.org/7q2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q2u RCSB], [https://www.ebi.ac.uk/pdbsum/7q2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q2u ProSAT]</span></td></tr> | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q2u OCA], [https://pdbe.org/7q2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q2u RCSB], [https://www.ebi.ac.uk/pdbsum/7q2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q2u ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/HINT1_HUMAN HINT1_HUMAN] Hydrolyzes adenosine 5'-monophosphoramidate substrates such as AMP-morpholidate, AMP-N-alanine methyl ester, AMP-alpha-acetyl lysine methyl ester and AMP-NH2 (By similarity). | |||
==See Also== | |||
*[[Histidine triad nucleotide-binding protein 3D structures|Histidine triad nucleotide-binding protein 3D structures]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Dolot RM]] | [[Category: Dolot RM]] | ||
[[Category: Strom AM]] | [[Category: Strom AM]] | ||
[[Category: Wagner CR]] | [[Category: Wagner CR]] | ||
Revision as of 11:19, 14 June 2023
The crystal structure of the HINT1 Q62A mutant.
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