5ewx: Difference between revisions

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<StructureSection load='5ewx' size='340' side='right'caption='[[5ewx]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
<StructureSection load='5ewx' size='340' side='right'caption='[[5ewx]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5ewx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EWX OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=5EWX FirstGlance]. <br>
<table><tr><td colspan='2'>[[5ewx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_virus_T4 Escherichia virus T4] and [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EWX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EYC:2,2-ETHYNE-1,2-DIYLBIS{5-[(CHLOROACETYL)AMINO]BENZENESULFONIC+ACID}'>EYC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">spa ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EYC:2,2-ETHYNE-1,2-DIYLBIS{5-[(CHLOROACETYL)AMINO]BENZENESULFONIC+ACID}'>EYC</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ewx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ewx OCA], [https://pdbe.org/5ewx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ewx RCSB], [https://www.ebi.ac.uk/pdbsum/5ewx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ewx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=5ewx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ewx OCA], [http://pdbe.org/5ewx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ewx RCSB], [http://www.ebi.ac.uk/pdbsum/5ewx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ewx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4]] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>
[https://www.uniprot.org/uniprot/SPA_STAAU SPA_STAAU] [https://www.uniprot.org/uniprot/ENLYS_BPT4 ENLYS_BPT4] Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer.<ref>PMID:22389108</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Escherichia virus T4]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lysozyme]]
[[Category: Staphylococcus aureus]]
[[Category: Jeong, W H]]
[[Category: Jeong WH]]
[[Category: Lee, H]]
[[Category: Lee H]]
[[Category: Lee, J O]]
[[Category: Lee JO]]
[[Category: Song, D H]]
[[Category: Song DH]]
[[Category: Alpha helix]]
[[Category: Cross-linker]]
[[Category: Ey-cb]]
[[Category: Fusion]]
[[Category: Protein binding]]
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