1xpi: Difference between revisions

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<StructureSection load='1xpi' size='340' side='right'caption='[[1xpi]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='1xpi' size='340' side='right'caption='[[1xpi]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1xpi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPI OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1XPI FirstGlance]. <br>
<table><tr><td colspan='2'>[[1xpi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XPI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XPI FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1v9k|1v9k]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">rluC ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xpi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpi OCA], [https://pdbe.org/1xpi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xpi RCSB], [https://www.ebi.ac.uk/pdbsum/1xpi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xpi ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pseudouridylate_synthase Pseudouridylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.70 4.2.1.70] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1xpi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xpi OCA], [http://pdbe.org/1xpi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xpi RCSB], [http://www.ebi.ac.uk/pdbsum/1xpi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xpi ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RLUC_ECOLI RLUC_ECOLI]] Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA.  
[https://www.uniprot.org/uniprot/RLUC_ECOLI RLUC_ECOLI] Responsible for synthesis of pseudouridine from uracil at positions 955, 2504 and 2580 in 23S ribosomal RNA.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus coli migula 1895]]
[[Category: Escherichia coli]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Pseudouridylate synthase]]
[[Category: Del Campo M]]
[[Category: Campo, M Del]]
[[Category: Fenna R]]
[[Category: Fenna, R]]
[[Category: Malhotra A]]
[[Category: Malhotra, A]]
[[Category: Ofengand J]]
[[Category: Ofengand, J]]
[[Category: Catalytic domain]]
[[Category: Lyase]]
[[Category: Pseudouridine synthase]]
[[Category: Rluc]]

Latest revision as of 06:48, 23 August 2023

Crystal structure of the catalytic domain of E. coli pseudouridine synthase RluC

1xpi, resolution 2.20Å

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