DNA Repair: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) No edit summary |
Ann Taylor (talk | contribs) mNo edit summary |
||
| Line 1: | Line 1: | ||
The discussion on this page is targeted at genetics students, so familiarity with [[DNA]] structure, [[DNA Replication]] and [[Basics of Protein Structure]] is assumed. | The discussion on this page is targeted at genetics students, so familiarity with [[DNA]] structure, [[DNA Replication]] and [[Basics of Protein Structure]] is assumed. | ||
'''DNA | '''DNA repair''' is necessary to maintain genome fidelity. Errors in DNA can arise from many different sources. Errors introduced in the replication process are the simplest source. This leads to non-Watson-Crick base pairs and local distortions in the helix. Bases can also be damaged by oxidizing agents, alkylating agents or UV light. This page will discuss different strategies for repairing these types of DNA damage. Click the green links to see depictions that match the words. | ||
<StructureSection load='2aor' size='350' side='right' scene='' caption='MutH complex with DNA, AMP derivative and Ca+2 ion (PDB id [[2aor]])'> | <StructureSection load='2aor' size='350' side='right' scene='' caption='MutH complex with DNA, AMP derivative and Ca+2 ion (PDB id [[2aor]])'> | ||
