3hm8: Difference between revisions

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<StructureSection load='3hm8' size='340' side='right'caption='[[3hm8]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
<StructureSection load='3hm8' size='340' side='right'caption='[[3hm8]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3hm8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HM8 FirstGlance]. <br>
<table><tr><td colspan='2'>[[3hm8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3HM8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3HM8 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BG6:BETA-D-GLUCOSE-6-PHOSPHATE'>BG6</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">HK3 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BG6:BETA-D-GLUCOSE-6-PHOSPHATE'>BG6</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Hexokinase Hexokinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.1 2.7.1.1] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hm8 OCA], [https://pdbe.org/3hm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hm8 RCSB], [https://www.ebi.ac.uk/pdbsum/3hm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hm8 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3hm8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3hm8 OCA], [https://pdbe.org/3hm8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3hm8 RCSB], [https://www.ebi.ac.uk/pdbsum/3hm8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3hm8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HXK3_HUMAN HXK3_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Hexokinase]]
[[Category: Homo sapiens]]
[[Category: Human]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Arrowsmith, C H]]
[[Category: Arrowsmith CH]]
[[Category: Bochkarev, A]]
[[Category: Bochkarev A]]
[[Category: Bountra, C]]
[[Category: Bountra C]]
[[Category: Edwards, A M]]
[[Category: Edwards AM]]
[[Category: Landry, R]]
[[Category: Landry R]]
[[Category: Nedyalkova, L]]
[[Category: Nedyalkova L]]
[[Category: Park, H]]
[[Category: Park H]]
[[Category: Rabeh, W]]
[[Category: Rabeh W]]
[[Category: Structural genomic]]
[[Category: Tempel W]]
[[Category: Tempel, W]]
[[Category: Tong Y]]
[[Category: Tong, Y]]
[[Category: Weigelt J]]
[[Category: Weigelt, J]]
[[Category: Allosteric enzyme]]
[[Category: Atp-binding]]
[[Category: Glucose]]
[[Category: Glucose-6-phosphate]]
[[Category: Glycolysis]]
[[Category: Kinase]]
[[Category: Non-protein kinase]]
[[Category: Nucleotide-binding]]
[[Category: Sgc]]
[[Category: Transferase]]

Latest revision as of 07:24, 6 September 2023

Crystal structure of the C-terminal Hexokinase domain of human HK3

3hm8, resolution 2.80Å

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