2d45: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older editNewer edit →
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
Line 3: Line 3:
<StructureSection load='2d45' size='340' side='right'caption='[[2d45]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
<StructureSection load='2d45' size='340' side='right'caption='[[2d45]], [[Resolution|resolution]] 3.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2d45]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/"micrococcus_aureus"_(rosenbach_1884)_zopf_1885 "micrococcus aureus" (rosenbach 1884) zopf 1885]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D45 FirstGlance]. <br>
<table><tr><td colspan='2'>[[2d45]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2D45 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2D45 FirstGlance]. <br>
</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1sd6|1sd6]], [[1sd7|1sd7]], [[1xsd|1xsd]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">mecI ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1280 "Micrococcus aureus" (Rosenbach 1884) Zopf 1885])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d45 OCA], [https://pdbe.org/2d45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d45 RCSB], [https://www.ebi.ac.uk/pdbsum/2d45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d45 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2d45 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2d45 OCA], [https://pdbe.org/2d45 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2d45 RCSB], [https://www.ebi.ac.uk/pdbsum/2d45 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2d45 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/MECI_STAAN MECI_STAAN]] Transcriptional repressor that constitutively blocks the transcription of the gene for the penicillin-binding protein MecA. Binds palindromic DNA with the sequence 5'-TACA-[AT]-N-TGTA-3'. Regulates genes involved in antibiotic resistance. Binds DNA as a dimer.  
[https://www.uniprot.org/uniprot/MECI_STAAN MECI_STAAN] Transcriptional repressor that constitutively blocks the transcription of the gene for the penicillin-binding protein MecA. Binds palindromic DNA with the sequence 5'-TACA-[AT]-N-TGTA-3'. Regulates genes involved in antibiotic resistance. Binds DNA as a dimer.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 35: Line 34:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Archer, G L]]
[[Category: Staphylococcus aureus]]
[[Category: Ko, T P]]
[[Category: Archer GL]]
[[Category: Musayev, F N]]
[[Category: Ko T-P]]
[[Category: Safo, M K]]
[[Category: Musayev FN]]
[[Category: Wang, A H.J]]
[[Category: Safo MK]]
[[Category: Zhao, Q]]
[[Category: Wang AH-J]]
[[Category: B-lactam]]
[[Category: Zhao Q]]
[[Category: Dimerization helical domain]]
[[Category: Methicillin]]
[[Category: Oligonucleotide binding domain]]
[[Category: Protein-dna complex]]
[[Category: Pseudo-dyad dna]]
[[Category: Repressor]]
[[Category: Transcription-dna complex]]
Retrieved from "https://proteopedia.org/2d45"