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<StructureSection load='3f8m' size='340' side='right'caption='[[3f8m]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3f8m' size='340' side='right'caption='[[3f8m]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[3f8m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycs2 Mycs2]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F8M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F8M FirstGlance]. <br>
<table><tr><td colspan='2'>[[3f8m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis_MC2_155 Mycolicibacterium smegmatis MC2 155]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3F8M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3F8M FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3f8l|3f8l]]</div></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">MSMEG_0650 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=246196 MYCS2])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f8m OCA], [https://pdbe.org/3f8m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f8m RCSB], [https://www.ebi.ac.uk/pdbsum/3f8m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f8m ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3f8m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3f8m OCA], [https://pdbe.org/3f8m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3f8m RCSB], [https://www.ebi.ac.uk/pdbsum/3f8m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3f8m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[https://www.uniprot.org/uniprot/PHNF_MYCS2 PHNF_MYCS2]] Represses the phnDCE operon, involved in the uptake of phosphate, under conditions of phosphate availability in the cell.<ref>PMID:18083811</ref>
[https://www.uniprot.org/uniprot/PHNF_MYCS2 PHNF_MYCS2] Represses the phnDCE operon, involved in the uptake of phosphate, under conditions of phosphate availability in the cell.<ref>PMID:18083811</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3f8m ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3f8m ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
==See Also==
*[[Transcriptional activator 3D structures|Transcriptional activator 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Mycs2]]
[[Category: Mycolicibacterium smegmatis MC2 155]]
[[Category: Baker, E N]]
[[Category: Baker EN]]
[[Category: Busby, J N]]
[[Category: Busby JN]]
[[Category: Cook, G M]]
[[Category: Cook GM]]
[[Category: Gebhard, S]]
[[Category: Gebhard S]]
[[Category: Lott, S J]]
[[Category: Lott SJ]]
[[Category: Money, V A]]
[[Category: Money VA]]
[[Category: Dna-binding]]
[[Category: Gntr]]
[[Category: Hutc]]
[[Category: Phnf]]
[[Category: Regulator]]
[[Category: Transcription]]
[[Category: Transcription regulation]]
[[Category: Utra]]
[[Category: Winged helix-turn-helix]]

Latest revision as of 15:28, 1 November 2023

Crystal Structure of PhnF from Mycobacterium smegmatis

3f8m, resolution 1.80Å

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