5mi7: Difference between revisions

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==BtGH84 mutant with covalent modification by MA4 in complex with PUGNAc==
==BtGH84 mutant with covalent modification by MA4 in complex with PUGNAc==
<StructureSection load='5mi7' size='340' side='right' caption='[[5mi7]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
<StructureSection load='5mi7' size='340' side='right'caption='[[5mi7]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5mi7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Bactn Bactn]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MI7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5MI7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5mi7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron_VPI-5482 Bacteroides thetaiotaomicron VPI-5482]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5MI7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5MI7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=7NT:~{N}-(4-morpholin-4-ylthieno[2,3-d]pyrimidin-2-yl)propanamide'>7NT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=OAN:O-(2-ACETAMIDO-2-DEOXY+D-GLUCOPYRANOSYLIDENE)+AMINO-N-PHENYLCARBAMATE'>OAN</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">BT_4395 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=226186 BACTN])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=7NT:~{N}-(4-morpholin-4-ylthieno[2,3-d]pyrimidin-2-yl)propanamide'>7NT</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=OAN:O-(2-ACETAMIDO-2-DEOXY+D-GLUCOPYRANOSYLIDENE)+AMINO-N-PHENYLCARBAMATE'>OAN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5mi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mi7 OCA], [http://pdbe.org/5mi7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5mi7 RCSB], [http://www.ebi.ac.uk/pdbsum/5mi7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5mi7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5mi7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5mi7 OCA], [https://pdbe.org/5mi7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5mi7 RCSB], [https://www.ebi.ac.uk/pdbsum/5mi7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5mi7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/OGA_BACTN OGA_BACTN]] Biological function unknown. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins.  
[https://www.uniprot.org/uniprot/OGA_BACTN OGA_BACTN] Biological function unknown. Capable of hydrolyzing the glycosidic link of O-GlcNAcylated proteins.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5mi7" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5mi7" style="background-color:#fffaf0;"></div>
==See Also==
*[[O-GlcNAcase|O-GlcNAcase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bactn]]
[[Category: Bacteroides thetaiotaomicron VPI-5482]]
[[Category: Darby, J F]]
[[Category: Large Structures]]
[[Category: Davies, G J]]
[[Category: Darby JF]]
[[Category: Hubbard, R E]]
[[Category: Davies GJ]]
[[Category: Activator]]
[[Category: Hubbard RE]]
[[Category: Hydrolase]]

Latest revision as of 18:44, 1 November 2023

BtGH84 mutant with covalent modification by MA4 in complex with PUGNAc

5mi7, resolution 2.10Å

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