7fi8: Difference between revisions
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== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[7fi8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FI8 FirstGlance]. <br> | <table><tr><td colspan='2'>[[7fi8]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7FI8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7FI8 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fi8 OCA], [https://pdbe.org/7fi8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fi8 RCSB], [https://www.ebi.ac.uk/pdbsum/7fi8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fi8 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7fi8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7fi8 OCA], [https://pdbe.org/7fi8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7fi8 RCSB], [https://www.ebi.ac.uk/pdbsum/7fi8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7fi8 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | == Function == | ||
[https://www.uniprot.org/uniprot/NKG2D_HUMAN NKG2D_HUMAN] Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes. | |||
==See Also== | |||
*[[NK cell receptor|NK cell receptor]] | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
Revision as of 17:16, 29 November 2023
Crystal structure of human MICA mutants in complex with natural killer cell receptor NKG2D
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