8qn5: Difference between revisions
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==M. tuberculosis salicylate synthase MbtI in complex with methyl-AMT (new crystal form)== | |||
<StructureSection load='8qn5' size='340' side='right'caption='[[8qn5]], [[Resolution|resolution]] 1.54Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[8qn5]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8QN5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8QN5 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.544Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0GA:3-{[(1Z)-1-CARBOXYPROP-1-EN-1-YL]OXY}-2-HYDROXYBENZOIC+ACID'>0GA</scene>, <scene name='pdbligand=FLC:CITRATE+ANION'>FLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NH4:AMMONIUM+ION'>NH4</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8qn5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8qn5 OCA], [https://pdbe.org/8qn5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8qn5 RCSB], [https://www.ebi.ac.uk/pdbsum/8qn5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8qn5 ProSAT]</span></td></tr> | ||
[[Category: Bellinzoni | </table> | ||
[[Category: Meneghetti | == Function == | ||
[[Category: Mori | [https://www.uniprot.org/uniprot/MBTI_MYCTU MBTI_MYCTU] Mediates the production of salicylate from chorismate via an isochorismate intermediate. Presents both isochorismate synthase and isochorismate-pyruvate lyase activities. Salycilate is the starter unit in the production of the virulence-conferring salicylate-based siderophore mycobactin.<ref>PMID:16923875</ref> | ||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mycobacterium tuberculosis H37Rv]] | |||
[[Category: Bellinzoni M]] | |||
[[Category: Meneghetti M]] | |||
[[Category: Mori M]] | |||
[[Category: Villa S]] | |||
Latest revision as of 09:05, 6 December 2023
M. tuberculosis salicylate synthase MbtI in complex with methyl-AMT (new crystal form)
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