8ud9: Difference between revisions

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'''Unreleased structure'''


The entry 8ud9 is ON HOLD  until Paper Publication
==Structure of human constitutive 20S proteasome complexed with the inhibitor TDI-8304==
 
<StructureSection load='8ud9' size='340' side='right'caption='[[8ud9]], [[Resolution|resolution]] 2.04&Aring;' scene=''>
Authors: Hsu, H.-C., Li, H.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8ud9]] is a 20 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8UD9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8UD9 FirstGlance]. <br>
Description: Structure of human constitutive 20S proteasome complexed with the inhibitor TDI-8304
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.04&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=YRE:(7S,10S,13S)-N-cyclopentyl-10-[2-(morpholin-4-yl)ethyl]-9,12-dioxo-13-(2-oxopyrrolidin-1-yl)-2-oxa-8,11-diazabicyclo[13.3.1]nonadeca-1(19),15,17-triene-7-carboxamide'>YRE</scene></td></tr>
[[Category: Li, H]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ud9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ud9 OCA], [https://pdbe.org/8ud9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ud9 RCSB], [https://www.ebi.ac.uk/pdbsum/8ud9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ud9 ProSAT]</span></td></tr>
[[Category: Hsu, H.-C]]
</table>
== Function ==
[https://www.uniprot.org/uniprot/PSA6_HUMAN PSA6_HUMAN] The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Hsu H-C]]
[[Category: Li H]]
Retrieved from "https://proteopedia.org/8ud9"