4lxk: Difference between revisions

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4lxk]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LXK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LXK FirstGlance]. <br>
<table><tr><td colspan='2'>[[4lxk]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4LXK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4LXK FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1YT:(1R,3S,4S,5R)-3-(4-AMINO-3-FLUORO-5-{[(2R)-1,1,1-TRIFLUORO-3-METHOXYPROPAN-2-YL]OXY}BENZYL)-5-[(3-TERT-BUTYLBENZYL)AMINO]TETRAHYDRO-2H-THIOPYRAN-4-OL+1-OXIDE'>1YT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1YT:(1R,3S,4S,5R)-3-(4-AMINO-3-FLUORO-5-{[(2R)-1,1,1-TRIFLUORO-3-METHOXYPROPAN-2-YL]OXY}BENZYL)-5-[(3-TERT-BUTYLBENZYL)AMINO]TETRAHYDRO-2H-THIOPYRAN-4-OL+1-OXIDE'>1YT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lxk OCA], [https://pdbe.org/4lxk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lxk RCSB], [https://www.ebi.ac.uk/pdbsum/4lxk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lxk ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4lxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4lxk OCA], [https://pdbe.org/4lxk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4lxk RCSB], [https://www.ebi.ac.uk/pdbsum/4lxk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4lxk ProSAT]</span></td></tr>
</table>
</table>

Latest revision as of 10:15, 30 October 2024

Crystal Structure of Human Beta Secretase in Complex with compound 11d

4lxk, resolution 2.05Å

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