1uk1: Difference between revisions

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[[Image:1uk1.gif|left|200px]]
[[Image:1uk1.gif|left|200px]]


{{Structure
<!--
|PDB= 1uk1 |SIZE=350|CAPTION= <scene name='initialview01'>1uk1</scene>, resolution 3.&Aring;
The line below this paragraph, containing "STRUCTURE_1uk1", creates the "Structure Box" on the page.
|SITE=
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
|LIGAND= <scene name='pdbligand=FRQ:5-FLUORO-1-[4-(4-PHENYL-3,6-DIHYDROPYRIDIN-1(2H)-YL)BUTYL]QUINAZOLINE-2,4(1H,3H)-DIONE'>FRQ</scene>
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/NAD(+)_ADP-ribosyltransferase NAD(+) ADP-ribosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.2.30 2.4.2.30] </span>
or leave the SCENE parameter empty for the default display.
|GENE=  
-->
|DOMAIN=
{{STRUCTURE_1uk1| PDB=1uk1  | SCENE= }}  
|RELATEDENTRY=[[1uk0|1UK0]]
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1uk1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1uk1 OCA], [http://www.ebi.ac.uk/pdbsum/1uk1 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1uk1 RCSB]</span>
}}


'''Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor'''
'''Crystal structure of human poly(ADP-ribose) polymerase complexed with a potent inhibitor'''
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Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase., Hattori K, Kido Y, Yamamoto H, Ishida J, Kamijo K, Murano K, Ohkubo M, Kinoshita T, Iwashita A, Mihara K, Yamazaki S, Matsuoka N, Teramura Y, Miyake H, J Med Chem. 2004 Aug 12;47(17):4151-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15293985 15293985]
Rational approaches to discovery of orally active and brain-penetrable quinazolinone inhibitors of poly(ADP-ribose)polymerase., Hattori K, Kido Y, Yamamoto H, Ishida J, Kamijo K, Murano K, Ohkubo M, Kinoshita T, Iwashita A, Mihara K, Yamazaki S, Matsuoka N, Teramura Y, Miyake H, J Med Chem. 2004 Aug 12;47(17):4151-4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15293985 15293985]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: NAD(+) ADP-ribosyltransferase]]
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Kinoshita, T.]]
[[Category: Kinoshita, T.]]
[[Category: protein-inhibitor complex]]
[[Category: Protein-inhibitor complex]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May  3 11:20:01 2008''
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 00:11:18 2008''
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