9m1h: Difference between revisions
From Proteopedia
Jump to navigationJump to search
m Protected "9m1h" [edit=sysop:move=sysop] |
No edit summary |
||
| Line 1: | Line 1: | ||
==Cryo-EM structure of PGE2-EP1-Gq complex== | |||
<StructureSection load='9m1h' size='340' side='right'caption='[[9m1h]], [[Resolution|resolution]] 2.55Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9m1h]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9M1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9M1H FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.55Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P2E:(Z)-7-[(1R,2R,3R)-3-HYDROXY-2-[(E,3S)-3-HYDROXYOCT-1-ENYL]-5-OXO-CYCLOPENTYL]HEPT-5-ENOIC+ACID'>P2E</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9m1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9m1h OCA], [https://pdbe.org/9m1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9m1h RCSB], [https://www.ebi.ac.uk/pdbsum/9m1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9m1h ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/PE2R1_HUMAN PE2R1_HUMAN] Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(q) proteins which activate a phosphatidylinositol-calcium second messenger system. May play a role as an important modulator of renal function. Implicated the smooth muscle contractile response to PGE2 in various tissues. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Meng X]] | |||
[[Category: Xu HE]] | |||
[[Category: Xu Y]] | |||
Latest revision as of 10:38, 30 April 2025
Cryo-EM structure of PGE2-EP1-Gq complex
| ||||||||||||
