7da7: Difference between revisions
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==== | ==Mouse Toll-like receptor 3 ectodomain in complex with lncRNA Rmrp in elongated form== | ||
<StructureSection load='7da7' size='340' side='right'caption='[[7da7]]' scene=''> | <StructureSection load='7da7' size='340' side='right'caption='[[7da7]], [[Resolution|resolution]] 3.47Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id= OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol= FirstGlance]. <br> | <table><tr><td colspan='2'>[[7da7]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7DA7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7DA7 FirstGlance]. <br> | ||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7da7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7da7 OCA], [https://pdbe.org/7da7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7da7 RCSB], [https://www.ebi.ac.uk/pdbsum/7da7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7da7 ProSAT]</span></td></tr> | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.47Å</td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7da7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7da7 OCA], [https://pdbe.org/7da7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7da7 RCSB], [https://www.ebi.ac.uk/pdbsum/7da7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7da7 ProSAT]</span></td></tr> | |||
</table> | </table> | ||
== Function == | |||
[https://www.uniprot.org/uniprot/TLR3_MOUSE TLR3_MOUSE] Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity).<ref>PMID:14993594</ref> | |||
==See Also== | |||
*[[Toll-like Receptor 3D structures|Toll-like Receptor 3D structures]] | |||
== References == | |||
<references/> | |||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Cao X]] | |||
[[Category: Li B]] | |||
Latest revision as of 05:55, 17 September 2025
Mouse Toll-like receptor 3 ectodomain in complex with lncRNA Rmrp in elongated form
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