8z8a: Difference between revisions

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'''Unreleased structure'''


The entry 8z8a is ON HOLD  until Paper Publication
==Cryo-EM structure of the Lactate-bound human HCAR1-Gi1 complex==
 
<StructureSection load='8z8a' size='340' side='right'caption='[[8z8a]], [[Resolution|resolution]] 2.82&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8z8a]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8Z8A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8Z8A FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.82&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=2OP:(2S)-2-HYDROXYPROPANOIC+ACID'>2OP</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8z8a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8z8a OCA], [https://pdbe.org/8z8a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8z8a RCSB], [https://www.ebi.ac.uk/pdbsum/8z8a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8z8a ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/HCAR1_HUMAN HCAR1_HUMAN] Acts as a receptor for L-lactate and mediates its anti-lipolytic effect through a G(i)-protein-mediated pathway.<ref>PMID:19047060</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Synthetic construct]]
[[Category: Gao M]]
[[Category: Ma X]]
[[Category: Mao C]]
[[Category: Zang S]]
[[Category: Zhang Y]]
[[Category: Zhu Y]]
Retrieved from "https://proteopedia.org/8z8a"