9sng: Difference between revisions
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==CTLH-CRA domain of murine RanBP10 mutant Q519G, F543L, Y548F and V556F== | |||
<StructureSection load='9sng' size='340' side='right'caption='[[9sng]], [[Resolution|resolution]] 1.74Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9sng]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9SNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9SNG FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.74Å</td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9sng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9sng OCA], [https://pdbe.org/9sng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9sng RCSB], [https://www.ebi.ac.uk/pdbsum/9sng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9sng ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/RBP10_MOUSE RBP10_MOUSE] May act as an adapter protein to couple membrane receptors to intracellular signaling pathways (By similarity). Enhances dihydrotestosterone-induced transactivation activity of AR, as well as dexamethasone-induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation (By similarity). Acts as a guanine nucleotide exchange factor (GEF) for RAN GTPase. May play an essential role in hemostasis and in maintaining microtubule dynamics with respect to both platelet shape and function.<ref>PMID:18347012</ref> <ref>PMID:19801445</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Mus musculus]] | |||
[[Category: Schindelin H]] | |||
[[Category: Van gen Hassend PM]] | |||
Latest revision as of 07:18, 18 February 2026
CTLH-CRA domain of murine RanBP10 mutant Q519G, F543L, Y548F and V556F
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