9wks: Difference between revisions
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==Crystal structure of hen egg-white lysozyme determined in the commissioning of NanoTerasu MX-ES== | |||
<StructureSection load='9wks' size='340' side='right'caption='[[9wks]], [[Resolution|resolution]] 1.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9wks]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9WKS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9WKS FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9wks FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9wks OCA], [https://pdbe.org/9wks PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9wks RCSB], [https://www.ebi.ac.uk/pdbsum/9wks PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9wks ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref> | |||
<div style="background-color:#fffaf0;"> | |||
== Publication Abstract from PubMed == | |||
Since the fiscal year 2022, ;Support Program for Life Science and Drug Discovery Research (BINDS Phase II)', funded by the Japan Agency for Medical Research and Development (AMED), has been supporting structural analysis research in Japan, promoting the further development of various advanced structural analysis technologies. The BINDS project aims to offer more timely and cutting-edge support by establishing a new macromolecular crystallography endstation (MX-ES) at NanoTerasu, Japan's first fourth-generation synchrotron-radiation facility. MX-ES has been equipped with microbeam focusing optics and a state-of-the-art measurement system for fully automated, high-throughput data collection from cooled crystals. Commissioning and initial experiments have been completed. User operations are expected to begin in the second half of the fiscal year 2025. | |||
A new macromolecular crystallography endstation at NanoTerasu for accelerating structural biology and drug discovery.,Yamada Y, Sakurai K, Fukuda A, Yamane H, Hatano T, Nakamura T, Ueno G, Masunaga T, Yamamoto M, Nango E Acta Crystallogr D Struct Biol. 2026 Jan 1;82(Pt 1):23-29. doi: , 10.1107/S2059798325011234. Epub 2026 Jan 1. PMID:41420545<ref>PMID:41420545</ref> | |||
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |||
[[Category: | </div> | ||
[[Category: | <div class="pdbe-citations 9wks" style="background-color:#fffaf0;"></div> | ||
[[Category: | == References == | ||
[[Category: Sakurai | <references/> | ||
[[Category: | __TOC__ | ||
[[Category: | </StructureSection> | ||
[[Category: Gallus gallus]] | |||
[[Category: Large Structures]] | |||
[[Category: Fukuda A]] | |||
[[Category: Nango E]] | |||
[[Category: Sakurai K]] | |||
[[Category: Yamada Y]] | |||
[[Category: Yamamoto M]] | |||
Latest revision as of 09:17, 11 March 2026
Crystal structure of hen egg-white lysozyme determined in the commissioning of NanoTerasu MX-ES
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