Phosphotransferase 3D structures: Difference between revisions

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**[[1c02]] - PT - yeast<br />
**[[1c02]] - PT - yeast<br />
**[[3our]] – PT IIA + pyruvate decarboxylase – ''Vibrio vulnificus''<BR />
**[[3our]] – PT IIA + pyruvate decarboxylase – ''Vibrio vulnificus''<BR />
**[[2l5h]], [[2kx9]] - EcPT I - ''Escherichia coli'' – NMR<BR />
**[[2kx9]], [[2l5h]] - EcPT I - ''Escherichia coli'' – NMR<BR />
**[[2xdf]] - EcPT I+ phosphocarrier protein HPR – NMR<BR />
**[[2xdf]] - EcPT I+ phosphocarrier protein HPR – NMR<BR />
**[[3oxp]] – PT II – ''Yersinia pestis''<BR />
**[[3oxp]] – PT II – ''Yersinia pestis''<BR />
Line 23: Line 23:


**[[3tyk]] - EcAGPT IA<BR />
**[[3tyk]] - EcAGPT IA<BR />
**[[3w0m]] - EcAGPT IA (mutant)<BR />
**[[3uzr]] - EcAGPT IB<BR />  
**[[3uzr]] - EcAGPT IB<BR />  
**[[3q2m]], [[3i1a]] – LpAGPT IA – ''Legionella pneumophila''<BR />
**[[3i1a]], [[3q2m]] – LpAGPT IA – ''Legionella pneumophila''<BR />
**[[1nd4]] – KpAGPT IIA – ''Klebsiella pneumoniae''<BR />
**[[1nd4]] – KpAGPT IIA – ''Klebsiella pneumoniae''<BR />
**[[1qhn]] – SvAGPT – ''Streptomyces venezuelae''<BR />
**[[1qhn]] – SvAGPT – ''Streptomyces venezuelae''<BR />
**[[3sgc]], [[3n4t]], [[3n4u]], [[3n4v]] ,[[4dbx]], [[4de4]]  - EncAGPT ID – ''Enterococcus casseliflavus''<BR />
**[[3n4t]], [[3n4u]], [[3n4v]], [[3sgc]], [[4dbx]], [[4de4]]  - EncAGPT ID – ''Enterococcus casseliflavus''<BR />
**[[1j7i]] - EfAGPT IIIA <br />
**[[1j7i]] - EfAGPT IIIA <br />
**[[4h05]], [[6fuc]] – PT VIII – ''Streptomyces rimosus''<br />
**[[4h05]], [[6fuc]] – PT VIII – ''Streptomyces rimosus''<br />
**[[4pdy]] – PT – ''Alicyclobacillus acidocaldarius''<br />
**[[4pdy]] – PT – ''Alicyclobacillus acidocaldarius''<br />
**[[6ef6]] – PT – ''Mycobacterium smegmatis''<br />
**[[6ef6]] – PT – ''Mycobacterium smegmatis''<br />
**[[9qoy]] – PaAG3’PT – Pseudomonas aeruginosa


*Aminoglycoside phosphotransferase complex with nucleotide
*Aminoglycoside phosphotransferase complex with nucleotide
Line 41: Line 43:
**[[1j7u]] - EfAGPT IIIA + AMP-PNP <br />
**[[1j7u]] - EfAGPT IIIA + AMP-PNP <br />
**[[4ej7]] - AGPT IA + ATP – ''Acinetobacter baumanii''<br />
**[[4ej7]] - AGPT IA + ATP – ''Acinetobacter baumanii''<br />
**[[4dt8]], [[4dt9]] - EncAGPT ID + nucleotide<br />
**[[4dt8]], [[4dt9]], [[4n57]] - EncAGPT IVA + nucleotide<br />
**[[4dta]], [[4dtb]] - EncAGPT ID (mutant) + nucleotide
**[[4dta]], [[4dtb]] - EncAGPT IVA (mutant) + nucleotide
**[[9o56]] - AGPT + ANP – Caldalkalibacillus thermarum<BR />
**[[5byl]] - SaAGPT IA + GMP-PCP – ''Staphylococcus aureus''<br />
**[[5iqa]] - SaAGPT IA + GMP-PNP <br />
**[[5iqh]], [[5iqi]], [[6ch4]] - SaAGPT IA (mutant) + GMP-PNP <br />
**[[5iqf]] - SaAGPT IA + GDP <br />
**[[3tdv]] – A2’’GPT IIIA + GDP – Enterococcus gallinarum<br />


*Aminoglycoside phosphotransferase complex with antibiotic
*Aminoglycoside phosphotransferase complex with antibiotic
Line 49: Line 57:
**[[3hav]] - EfAGPT + ATP + antibiotic <BR />
**[[3hav]] - EfAGPT + ATP + antibiotic <BR />
**[[3tm0]] - EfAGPT + AMP-PNP + antibiotic<br />
**[[3tm0]] - EfAGPT + AMP-PNP + antibiotic<br />
**[[2b0q]], [[1l8t]] - EfAGPT IIIA + ADP + antibiotic<br />
**[[1l8t]], [[2b0q]] - EfAGPT IIIA + ADP + antibiotic<br />
**[[1grq]], [[1grr]], [[1qhs]] - SvAGPT + antibiotic<br />  
**[[1grq]], [[1grr]], [[1qhs]] - SvAGPT + antibiotic<br />  
**[[1qhy]] - SvAGPT + ATPγ + antibiotic<br />
**[[1qhy]] - SvAGPT + ATPγ + antibiotic<br />
Line 56: Line 64:
**[[4feu]], [[4fev]], [[4few]], [[4fex]], [[4gkh]], [[4gki]] - LpAGPT IA + inhibitor + antibiotic<br />
**[[4feu]], [[4fev]], [[4few]], [[4fex]], [[4gkh]], [[4gki]] - LpAGPT IA + inhibitor + antibiotic<br />
**[[6fux]] - SrAGPT + ADP + antibiotic<br />
**[[6fux]] - SrAGPT + ADP + antibiotic<br />
**[[6o18]] - EcAGPT IA (mutant) + antibiotic<br />
**[[3w0o]], [[3w0p]] - EcAGPT IA (mutant) + ADP + antibiotic<br />
**[[3w0s]] - EcAGPT IA + AMP-PNP + antibiotic<br />
**[[3w0n]], [[3w0q]], [[3w0r]] - EcAGPT IA (mutant) + AMP-PNP + antibiotic<br />
**[[5iqg]] - SaAGPT IA + GDP + antibiotic <br />
**[[5iqb]], [[5iqc]], [[5iqd]], [[5iqe]], [[6c5u]], [[6cav]], [[6cey]], [[6cgd]], [[6cgg]] - SaAGPT IA + GMP-PNP + antibiotic <br />
**[[6iy9]] - AGPT IA (mutant) + antibiotic – Streptomyces hygroscopicus<BR />
**[[6ctz]] – A2’’GPT IIIA + GDP + antibiotic <br />


*Aminoglycoside phosphotransferase complex with inhibitor
*Aminoglycoside phosphotransferase complex with inhibitor


**[[2bkk]], [[3q2j]] - EfAGPT IIIA + inhibitor
**[[2bkk]], [[3q2j]] - EfAGPT IIIA + inhibitor
**[[9qos]] – PaAG3’PT + inhibitor


*'''Phosphoenolpyruvate-protein phosphotransferase'''
*'''Phosphoenolpyruvate-protein phosphotransferase'''
Line 71: Line 88:
**[[1o53]] - EcPEP glucose-specific IIA N terminal – NMR<br />
**[[1o53]] - EcPEP glucose-specific IIA N terminal – NMR<br />
**[[3eye]] - EcPEP acetylgalactosamine-specific IIB<br />
**[[3eye]] - EcPEP acetylgalactosamine-specific IIB<br />
**[[2oq3]], [[1vrv]] - EcPEP mannitol-specific IIA<br />
**[[1vrv]], [[2oq3]] - EcPEP mannitol-specific IIA<br />
**[[1vkr]] - EcPEP mannitol-specific IIABC – NMR<br />
**[[1vkr]] - EcPEP mannitol-specific IIABC – NMR<br />
**[[2few]] - EcPEP mannitol-specific IIA (mutant)<br />
**[[2few]] - EcPEP mannitol-specific IIA (mutant)<br />
Line 82: Line 99:
**[[1nrz]] - KpPEP sorbose-specific IIB<br />
**[[1nrz]] - KpPEP sorbose-specific IIB<br />
**[[2hro]] – PEP – ''Staphylococcus carnosus''<br />
**[[2hro]] – PEP – ''Staphylococcus carnosus''<br />
**[[2wqd]] - PEP (mutant) – ''Staphylococcus aureus''<br />
**[[2wqd]] - SaPEP (mutant) <br />
**[[3trc]] - PEP (mutant) – ''Coxiella burnetii''<br />
**[[3trc]] - PEP (mutant) – ''Coxiella burnetii''<br />
**[[5woy]] - PEP – ''Caldanaerobacter subterraneus'' - NMR<br />
**[[5woy]] - PEP – ''Caldanaerobacter subterraneus'' - NMR<br />
Line 93: Line 110:
**[[2xz7]] – TtPEP PEP-binding domain + phosphoenolpyruvate – ''Thermoanaerobacter tengcongensis''<BR />
**[[2xz7]] – TtPEP PEP-binding domain + phosphoenolpyruvate – ''Thermoanaerobacter tengcongensis''<BR />
**[[2xz9]] - TtPEP PEP-binding domain + pyruvate<BR />
**[[2xz9]] - TtPEP PEP-binding domain + pyruvate<BR />
**[[1ggr ]]- EcPEP glucose-specific IIA + phosphocarrier protein HPR – NMR<br />
**[[1ggr]] - EcPEP glucose-specific IIA + phosphocarrier protein HPR – NMR<br />
**[[3bp8]] - EcPEP glucose-specific IIB + NAGC-like transcriptional regulator<br />
**[[3bp8]] - EcPEP glucose-specific IIB + NAGC-like transcriptional regulator<br />
**[[1j6t]] - EcPEP mannitol-specific IIABC + phosphocarrier protein HPR – NMR<br />
**[[1j6t]] - EcPEP mannitol-specific IIABC + phosphocarrier protein HPR – NMR<br />
Line 104: Line 121:
**[[1f51]] – BsSpo0B + Spo0F<br />  
**[[1f51]] – BsSpo0B + Spo0F<br />  
**[[2ftk]] – BsSpo0B + Spo0F (mutant)<br />
**[[2ftk]] – BsSpo0B + Spo0F (mutant)<br />
**[[1pey]], [[1nat]] – BsPT Spo0F<br />
**[[1nat]], [[1pey]] – BsPT Spo0F<br />
**[[1srr]] - BsPT Spo0F (mutant) <br />
**[[1srr]] - BsPT Spo0F (mutant) <br />
**[[1pux]], [[1fsp]], [[2fsp]] - BsPT Spo0F – NMR<br />
**[[1fsp]], [[1pux]], [[2fsp]] - BsPT Spo0F – NMR<br />
**[[2jvi]], [[2jvj]], [[2jvk]] - BsPT Spo0F (mutant) – NMR<br />
**[[2jvi]], [[2jvj]], [[2jvk]] - BsPT Spo0F (mutant) – NMR<br />
**[[3q15]] - BsPT spo0F + response regulator aspartate phosphatase<br />
**[[3q15]] - BsPT spo0F + response regulator aspartate phosphatase<br />
Line 116: Line 133:
**[[5igi]], [[5igj]], [[5igs]], [[5igt]] – EcMPT I  + antibiotic + guanosine<br />
**[[5igi]], [[5igj]], [[5igs]], [[5igt]] – EcMPT I  + antibiotic + guanosine<br />
**[[5igp]], [[5igr]] – EcMPT I  + antibiotic + GDP<br />
**[[5igp]], [[5igr]] – EcMPT I  + antibiotic + GDP<br />
**[[5uxa]], [[5igu]] – EcMPT II <br />
**[[5igu]], [[5uxa]] – EcMPT II <br />
**[[5iwu]] – EcMPT II  + antibiotic<br />
**[[5iwu]] – EcMPT II  + antibiotic<br />
**[[5ih1]], [[5igv]], [[5igw]], [[5igy]], [[5igz]] – EcMPT II  + antibiotic + GDP<br />
**[[5igv]], [[5igw]], [[5igy]], [[5igz]], [[5ih1]] – EcMPT II  + antibiotic + GDP<br />
**[[5ih0]] – EcMPT II (mutant) + antibiotic + GDP<br />  
**[[5ih0]] – EcMPT II (mutant) + antibiotic + GDP<br />  
**[[5uxb]] – BfMPT II – ''Brachybacterium faecium'' <br />  
**[[5uxb]] – BfMPT II – ''Brachybacterium faecium'' <br />  
**[[5uxd]] – BfMPT II  + antibiotic<br />  
**[[5uxd]] – BfMPT II  + antibiotic<br />
**[[5uxc]] – BfMPT II  + GDP<br />
**[[7w19]] – AbMPT <br />
**[[7w19]] – AbMPT <br />
**[[7w1a]] – AbMPT  + antibiotic + GMP<br />
**[[7w1a]] – AbMPT  + antibiotic + GMP<br />
**[[7w15]] – AbMPT  + antibiotic + GTP<br />
**[[7w15]] – AbMPT  + antibiotic + GTP<br />
**[[8ixi]] – KpMPT <br />


*'''Polyphosphate:AMP phosphotransferase or polyphosphate kinase'''
*'''Polyphosphate:AMP phosphotransferase or polyphosphate kinase or ATP-polyphosphate phosphotransferase or PPK1 or polyphosphate--nucleotide phosphotransferase or polyphosphate kinase '''


**[[5lc9]] – MrPAPT – ''Meiothermus ruber'' <br />  
**[[5lc9]] – MrPAPT – ''Meiothermus ruber'' <br />  
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**[[5ldb]], [[5maq]] – MrPAPT + ADP <br />
**[[5ldb]], [[5maq]] – MrPAPT + ADP <br />
**[[6dzg]] – PAPT + ADP – ''Rhizobium meliloti''<br />
**[[6dzg]] – PAPT + ADP – ''Rhizobium meliloti''<br />
**[[6au0]], [[6aqn]] – ChPAPT + inhibitor – ''Cytophaga hutchinsonii'' <br />
**[[6aqn]], [[6au0]] – ChPAPT + inhibitor – ''Cytophaga hutchinsonii'' <br />
**[[6anh]] – ChPAPT + guanosine tetraphosphate <br />
**[[6anh]] – ChPAPT + guanosine tetraphosphate <br />
**[[6ang]] – ChPAPT + AMP <br />
**[[6ang]] – ChPAPT + AMP <br />
**[[6an9]] – ChPAPT + ADP <br />
**[[6an9]] – ChPAPT + ADP <br />
**[[9uri]] – EcPPK1 – Cryo EM<br />
**[[9urj]] – EcPPK1 + tetraphosphate – Cryo EM<br />
**[[1xdo]], [[1xdp]] – EcPPK1 + AMP-PNP <br />
**[[9gia]] – PPK2 + pyrophosphate – Bacillus cereus<br />
**[[9igq]], [[9igr]] – PAPT + polyphosphate – Erysipelotrichdeae bacterium <br />


*'''Rifampin phosphotransferase'''  
*'''Rifampin phosphotransferase'''  
Line 146: Line 170:
**[[5hv3]] – LmPAPT (mutant) + AMPPNP<br />
**[[5hv3]] – LmPAPT (mutant) + AMPPNP<br />
**[[5hv1]] – LmPAPT + AMPPNP + rifampin<br />
**[[5hv1]] – LmPAPT + AMPPNP + rifampin<br />
**[[5fbs]] – LmPAPT + ADP <br />
**[[5fbt]], [[5fbu]] – LmPAPT + rifampin<br />


*'''CDP-alcohol phosphotransferase'''  
*'''CDP-alcohol phosphotransferase'''  
Line 159: Line 185:
**[[7f0b]] – SmPAPT + ATP <br />
**[[7f0b]] – SmPAPT + ATP <br />


*'''N-acetylglucosamine-1-phosphotransferase'''  
*'''N-acetylglucosamine-1-phosphotransferase or GlcNAc-1-phosphotransferase'''  


**[[7s05]], [[7s06]] – hPAPT alpha+beta subunits – Cryo EM<br />
**[[7s05]], [[7s06]] – hPAPT alpha+beta subunits – Cryo EM<br />
**[[2n6d]] – hPAPT alpha+beta subunits 140-315 – NMR<br />
**[[2n6d]] – hPAPT alpha+beta subunits 140-315 – NMR<br />
**[[9bgg]] – hPAPT – Cryo EM<br />
**[[9bgf]] – hPAPT + UDP-GlcNAc – Cryo EM<br />
**[[7s69]] – fPAPT gamma subunit - frog<br />
**[[7s69]] – fPAPT gamma subunit - frog<br />
**[[7s6n]] – zPAPT alpha+beta subunits + NAG – zebrafish<br />
**[[7s6n]] – zPAPT alpha+beta subunits + NAG – zebrafish<br />
**[[7sj2]] – zPAPT alpha+beta subunits + NAG + UDP-GlcNAc<br />
**[[7sj2]] – zPAPT alpha+beta subunits + NAG + UDP-GlcNAc<br />
**[[7dxi]] – PAPT – Drosophila melanogaster - Cryo EM<br />
*'''UDP-MurNAc-pentapeptide phosphotransferase'''
**[[4j72]]  – AaPAPT - Aquifex aeolicus<br />
**[[5ckr]], [[5jnq]], [[6oyh]], [[6oyz]], [[6oz6]], [[8cxr]] – AaPAPT + inhibitor<br />
**[[9b70]], [[9b71]] – AaPAPT + nanobody – Cryo EM<br />
**[[8g01]], [[8g02]]  – EcPAPT + GPE + SlyD – Cryo EM<br />
*'''tRNA 2’-phosphotransferase 1'''
**[[7yw3]] – hPAPT <br />
**[[7yw2]] – mPAPT <br />
**[[7yw4]] – yPAPT <br />
**[[7kw8]] – RsPAPT - NMR<br />
**[[7kw9]] – RsPAPT + NAD - NMR<br />
**[[6e3a]], [[6ede]] – PAPT – Acetivibrio thermocellus<br />
**[[8tg6]] – PpPAPT – Pyrococcus pernix<br />
**[[8tg3]] – PpPAPT + ADP-ribose-1”-phosphate <br />
**[[8tg4]] – PpPAPT + ADP-ribose-2”-phosphate + RNA<br />
**[[8tfi]] – PhPAPT – Pyrococcus horikishii<br />
**[[8tfx]] – PhPAPT + ADP<br />
**[[8tkb]] – PhPAPT + AMP<br />
**[[8tg5]] – PhPAPT + PO4 RNA<br />
**[[8tfz]] – PhPAPT + NAD<br />
**[[8tfxy] – PhPAPT + NADP<br />


*'''ATP:AMP phosphotransferase''' see [[Adenylate kinase]]
*'''ATP:AMP phosphotransferase''' see [[Adenylate kinase]]
*'''GTP:AMP phosphotransferase''' see [[Adenylate kinase]]
*'''ATP:glycerol 3-phosphotransferase''' see [[Glycerol kinase]]


}}
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