Phosphotransferase 3D structures

3D structures of phosphotransferase

Updated on 17-May-2026

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• Phosphotransferase
  • 1fyn – PT fyn SH3 domain + polyproline peptide - human
    
  • 1c02 - PT - yeast
    
  • 3our – PT IIA + pyruvate decarboxylase – Vibrio vulnificus
    
  • 2kx9, 2l5h - EcPT I - Escherichia coli – NMR
    
  • 2xdf - EcPT I+ phosphocarrier protein HPR – NMR
    
  • 3oxp – PT II – Yersinia pestis
    
  • 3ci6 – PT GAF domain – Acinetobacter
    
  • 2ooc, 4fpp – PT histidine – Caulobacter crescentus
    
  • 3ipj – PT IIABC – Clostridium difficile
    
  • 2f9h - EfPT IIA – Enterococcus faecalis
    
  • 3n9x – PT – Plasmodium berghei
    
  • 4qpk – BaPT – Brucella abortus
    
  • 4qpj – BaPT + CTRA
    
• Aminoglycoside phosphotransferase
  • 3tyk - EcAGPT IA
    
  • 3w0m - EcAGPT IA (mutant)
    
  • 3uzr - EcAGPT IB
    
  • 3i1a, 3q2m – LpAGPT IA – Legionella pneumophila
    
  • 1nd4 – KpAGPT IIA – Klebsiella pneumoniae
    
  • 1qhn – SvAGPT – Streptomyces venezuelae
    
  • 3n4t, 3n4u, 3n4v, 3sgc, 4dbx, 4de4 - EncAGPT ID – Enterococcus casseliflavus
    
  • 1j7i - EfAGPT IIIA
    
  • 4h05, 6fuc – PT VIII – Streptomyces rimosus
    
  • 4pdy – PT – Alicyclobacillus acidocaldarius
    
  • 6ef6 – PT – Mycobacterium smegmatis
    
  • 9qoy – PaAG3’PT – Pseudomonas aeruginosa
• Aminoglycoside phosphotransferase complex with nucleotide
  • 4dca - EcAGPT IB + ADP
    
  • 1qhx - SvAGPT + ATP
    
  • 3i0q - LpAGPT IA + AMP
    
  • 1j7l - EfAGPT IIIA + ADP
    
  • 1j7u - EfAGPT IIIA + AMP-PNP
    
  • 4ej7 - AGPT IA + ATP – Acinetobacter baumanii
    
  • 4dt8, 4dt9, 4n57 - EncAGPT IVA + nucleotide
    
  • 4dta, 4dtb - EncAGPT IVA (mutant) + nucleotide
  • 9o56 - AGPT + ANP – Caldalkalibacillus thermarum
    
  • 5byl - SaAGPT IA + GMP-PCP – Staphylococcus aureus
    
  • 5iqa - SaAGPT IA + GMP-PNP
    
  • 5iqh, 5iqi, 6ch4 - SaAGPT IA (mutant) + GMP-PNP
    
  • 5iqf - SaAGPT IA + GDP
    
  • 3tdv – A2’’GPT IIIA + GDP – Enterococcus gallinarum
    
• Aminoglycoside phosphotransferase complex with antibiotic
  • 3ham - EfAGPT + antibiotic
    
  • 3hav - EfAGPT + ATP + antibiotic
    
  • 3tm0 - EfAGPT + AMP-PNP + antibiotic
    
  • 1l8t, 2b0q - EfAGPT IIIA + ADP + antibiotic
    
  • 1grq, 1grr, 1qhs - SvAGPT + antibiotic
    
  • 1qhy - SvAGPT + ATPγ + antibiotic
    
  • 3sg8, 3sg9, 4dfb, 4dfu - EncAGPT ID + antibiotic
    
  • 3i0o - LpAGPT IA + ADP + antibiotic
    
  • 4feu, 4fev, 4few, 4fex, 4gkh, 4gki - LpAGPT IA + inhibitor + antibiotic
    
  • 6fux - SrAGPT + ADP + antibiotic
    
  • 6o18 - EcAGPT IA (mutant) + antibiotic
    
  • 3w0o, 3w0p - EcAGPT IA (mutant) + ADP + antibiotic
    
  • 3w0s - EcAGPT IA + AMP-PNP + antibiotic
    
  • 3w0n, 3w0q, 3w0r - EcAGPT IA (mutant) + AMP-PNP + antibiotic
    
  • 5iqg - SaAGPT IA + GDP + antibiotic
    
  • 5iqb, 5iqc, 5iqd, 5iqe, 6c5u, 6cav, 6cey, 6cgd, 6cgg - SaAGPT IA + GMP-PNP + antibiotic
    
  • 6iy9 - AGPT IA (mutant) + antibiotic – Streptomyces hygroscopicus
    
  • 6ctz – A2’’GPT IIIA + GDP + antibiotic
    
• Aminoglycoside phosphotransferase complex with inhibitor
  • 2bkk, 3q2j - EfAGPT IIIA + inhibitor
  • 9qos – PaAG3’PT + inhibitor
• Phosphoenolpyruvate-protein phosphotransferase
  • 2hwg - EcPEP
    
  • 5t12 - EcPEP N terminal (mutant)
    
  • 6v9k, 6vbj, 6vu0 - EcPEP C terminal (mutant)
    
  • 2kyr – EcPEP fructose-specific IIB
    
  • 1vsq, 2jzh, 2jzn, 2jzo - EcPEP mannose-specific IIA - NMR
    
  • 3bp3 - EcPEP glucose-specific IIB
    
  • 1o53 - EcPEP glucose-specific IIA N terminal – NMR
    
  • 3eye - EcPEP acetylgalactosamine-specific IIB
    
  • 1vrv, 2oq3 - EcPEP mannitol-specific IIA
    
  • 1vkr - EcPEP mannitol-specific IIABC – NMR
    
  • 2few - EcPEP mannitol-specific IIA (mutant)
    
  • 1wcr - EcPEP diacetylchitobiose-specific IIA (mutant) – NMR
    
  • 1h9c - EcPEP diacetylchitobiose-specific IIB – NMR
    
  • 2r4q - BsPEP fructose-specific IIABC – Bacillus subtilis
    
  • 2r48 - BsPEP fructose-specific IIB
    
  • 3ipr – EfPEP gluconate-specific IIA
    
  • 3bed - EfPEP mannose-specific IIA
    
  • 1nrz - KpPEP sorbose-specific IIB
    
  • 2hro – PEP – Staphylococcus carnosus
    
  • 2wqd - SaPEP (mutant)
    
  • 3trc - PEP (mutant) – Coxiella burnetii
    
  • 5woy - PEP – Caldanaerobacter subterraneus - NMR
    
  • 3nbm – PEP lactose-specific IIBC – Streptococcus pneumoniae
    
  • 2l2q - PEP cellbiose-specific IIB – Borrelia burgdorferi – NMR
    
  • 3k1s - PEP cellbiose-specific IIA – Bacillus anthracis
    
• Phosphoenolpyruvate-protein phosphotransferase complex
  • 2xz7 – TtPEP PEP-binding domain + phosphoenolpyruvate – Thermoanaerobacter tengcongensis
    
  • 2xz9 - TtPEP PEP-binding domain + pyruvate
    
  • 1ggr - EcPEP glucose-specific IIA + phosphocarrier protein HPR – NMR
    
  • 3bp8 - EcPEP glucose-specific IIB + NAGC-like transcriptional regulator
    
  • 1j6t - EcPEP mannitol-specific IIABC + phosphocarrier protein HPR – NMR
    
  • 5t1o - EcPEP + phosphocarrier protein NPR
    
  • 2mp0 – EcPEP N terminal + EcPEP glucose-specific IIA
    
  • 4jbw – EcPEP glucose-specific IIA + Malf + Malg + Malk
    
• Sporulation initiation phosphotransferase
  • 1f51 – BsSpo0B + Spo0F
    
  • 2ftk – BsSpo0B + Spo0F (mutant)
    
  • 1nat, 1pey – BsPT Spo0F
    
  • 1srr - BsPT Spo0F (mutant)
    
  • 1fsp, 1pux, 2fsp - BsPT Spo0F – NMR
    
  • 2jvi, 2jvj, 2jvk - BsPT Spo0F (mutant) – NMR
    
  • 3q15 - BsPT spo0F + response regulator aspartate phosphatase
    
  • 6ifh – SpoF - Paenisporosarcina
    
• Microlide 2'-phosphotransferase
  • 5igh – EcMPT I
    
  • 5igi, 5igj, 5igs, 5igt – EcMPT I + antibiotic + guanosine
    
  • 5igp, 5igr – EcMPT I + antibiotic + GDP
    
  • 5igu, 5uxa – EcMPT II
    
  • 5iwu – EcMPT II + antibiotic
    
  • 5igv, 5igw, 5igy, 5igz, 5ih1 – EcMPT II + antibiotic + GDP
    
  • 5ih0 – EcMPT II (mutant) + antibiotic + GDP
    
  • 5uxb – BfMPT II – Brachybacterium faecium
    
  • 5uxd – BfMPT II + antibiotic
    
  • 5uxc – BfMPT II + GDP
    
  • 7w19 – AbMPT
    
  • 7w1a – AbMPT + antibiotic + GMP
    
  • 7w15 – AbMPT + antibiotic + GTP
    
  • 8ixi – KpMPT
    
• Polyphosphate:AMP phosphotransferase or polyphosphate kinase or ATP-polyphosphate phosphotransferase or PPK1 or polyphosphate--nucleotide phosphotransferase or polyphosphate kinase
  • 5lc9 – MrPAPT – Meiothermus ruber
    
  • 5o6k – MrPAPT (mutant)
    
  • 5lcd – MrPAPT + AMP
    
  • 5ld1 – MrPAPT + ATP
    
  • 5o6m – MrPAPT (mutant) + ATP
    
  • 5ldb, 5maq – MrPAPT + ADP
    
  • 6dzg – PAPT + ADP – Rhizobium meliloti
    
  • 6aqn, 6au0 – ChPAPT + inhibitor – Cytophaga hutchinsonii
    
  • 6anh – ChPAPT + guanosine tetraphosphate
    
  • 6ang – ChPAPT + AMP
    
  • 6an9 – ChPAPT + ADP
    
  • 9uri – EcPPK1 – Cryo EM
    
  • 9urj – EcPPK1 + tetraphosphate – Cryo EM
    
  • 1xdo, 1xdp – EcPPK1 + AMP-PNP
    
  • 9gia – PPK2 + pyrophosphate – Bacillus cereus
    
  • 9igq, 9igr – PAPT + polyphosphate – Erysipelotrichdeae bacterium
    
• Rifampin phosphotransferase
  • 5hv6 – LmPAPT – Listeria monocytogenes
    
  • 5hv2 – LmPAPT (mutant)
    
  • 5hv3 – LmPAPT (mutant) + AMPPNP
    
  • 5hv1 – LmPAPT + AMPPNP + rifampin
    
  • 5fbs – LmPAPT + ADP
    
  • 5fbt, 5fbu – LmPAPT + rifampin
    
• CDP-alcohol phosphotransferase
  • 4q7c – AfPAPT – Archaeoglobus fulgidus
    
  • 4o6n – AfPAPT + CDP
    
  • 4o6m – AfPAPT + CMP
    
• Capreomycin phosphotransferase
  • 7f0a – SmPAPT – Saccharothrix mutabilis
    
  • 7f0c, 7f0f – SmPAPT + CMM
    
  • 7f0b – SmPAPT + ATP
    
• N-acetylglucosamine-1-phosphotransferase or GlcNAc-1-phosphotransferase
  • 7s05, 7s06 – hPAPT alpha+beta subunits – Cryo EM
    
  • 2n6d – hPAPT alpha+beta subunits 140-315 – NMR
    
  • 9bgg – hPAPT – Cryo EM
    
  • 9bgf – hPAPT + UDP-GlcNAc – Cryo EM
    
  • 7s69 – fPAPT gamma subunit - frog
    
  • 7s6n – zPAPT alpha+beta subunits + NAG – zebrafish
    
  • 7sj2 – zPAPT alpha+beta subunits + NAG + UDP-GlcNAc
    
  • 7dxi – PAPT – Drosophila melanogaster - Cryo EM
    
• UDP-MurNAc-pentapeptide phosphotransferase
  • 4j72 – AaPAPT - Aquifex aeolicus
    
  • 5ckr, 5jnq, 6oyh, 6oyz, 6oz6, 8cxr – AaPAPT + inhibitor
    
  • 9b70, 9b71 – AaPAPT + nanobody – Cryo EM
    
  • 8g01, 8g02 – EcPAPT + GPE + SlyD – Cryo EM
    
• tRNA 2’-phosphotransferase 1
  • 7yw3 – hPAPT
    
  • 7yw2 – mPAPT
    
  • 7yw4 – yPAPT
    
  • 7kw8 – RsPAPT - NMR
    
  • 7kw9 – RsPAPT + NAD - NMR
    
  • 6e3a, 6ede – PAPT – Acetivibrio thermocellus
    
  • 8tg6 – PpPAPT – Pyrococcus pernix
    
  • 8tg3 – PpPAPT + ADP-ribose-1”-phosphate
    
  • 8tg4 – PpPAPT + ADP-ribose-2”-phosphate + RNA
    
  • 8tfi – PhPAPT – Pyrococcus horikishii
    
  • 8tfx – PhPAPT + ADP
    
  • 8tkb – PhPAPT + AMP
    
  • 8tg5 – PhPAPT + PO4 RNA
    
  • 8tfz – PhPAPT + NAD
    
  • 8tfy – PhPAPT + NADP
    
• ATP:AMP phosphotransferase see Adenylate kinase
• GTP:AMP phosphotransferase see Adenylate kinase
• ATP:glycerol 3-phosphotransferase see Glycerol kinase

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel