9w0l: Difference between revisions
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==S1P3 in complex with CYM52581 and spm242== | |||
<StructureSection load='9w0l' size='340' side='right'caption='[[9w0l]], [[Resolution|resolution]] 3.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[9w0l]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Niallia_circulans Niallia circulans]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9W0L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9W0L FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.6Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A1EUC:[(2~{R})-2-azanyl-4-[2-chloranyl-4-(3-hydroxyphenyl)sulfanyl-phenyl]-2-(hydroxymethyl)butyl]+dihydrogen+phosphate'>A1EUC</scene>, <scene name='pdbligand=A1EUD:~{N}-[(~{R})-(5-bromanylpyridin-2-yl)-(3,4-dichlorophenyl)methyl]-4-cyano-3-fluoranyl-benzamide'>A1EUD</scene></td></tr> | ||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9w0l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9w0l OCA], [https://pdbe.org/9w0l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9w0l RCSB], [https://www.ebi.ac.uk/pdbsum/9w0l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9w0l ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
[[Category: Beili | == Function == | ||
[https://www.uniprot.org/uniprot/XYNA_NIACI XYNA_NIACI] [https://www.uniprot.org/uniprot/S1PR3_HUMAN S1PR3_HUMAN] Receptor for the lysosphingolipid sphingosine 1-phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. When expressed in rat HTC4 hepatoma cells, is capable of mediating S1P-induced cell proliferation and suppression of apoptosis.<ref>PMID:10617617</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Niallia circulans]] | |||
[[Category: Beili W]] | |||
[[Category: Qiang Z]] | |||
[[Category: Qiuxiang T]] | |||
Latest revision as of 06:57, 3 June 2026
S1P3 in complex with CYM52581 and spm242
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