13eu: Difference between revisions
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==Cryo-EM structure of HAdV-C6 hexon trimer in complex with human coagulation factor X (FX)== | |||
<StructureSection load='13eu' size='340' side='right'caption='[[13eu]], [[Resolution|resolution]] 3.26Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[13eu]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Human_adenovirus_6 Human adenovirus 6]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=13EU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=13EU FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.26Å</td></tr> | |||
[[Category: | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CGU:GAMMA-CARBOXY-GLUTAMIC+ACID'>CGU</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=13eu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=13eu OCA], [https://pdbe.org/13eu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=13eu RCSB], [https://www.ebi.ac.uk/pdbsum/13eu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=13eu ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/B2ZWX4_ADE06 B2ZWX4_ADE06] Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus.[ARBA:ARBA00024662][HAMAP-Rule:MF_04051] | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Human adenovirus 6]] | |||
[[Category: Large Structures]] | |||
[[Category: Ma OX]] | |||
[[Category: Reddy VS]] | |||
Latest revision as of 07:16, 8 July 2026
Cryo-EM structure of HAdV-C6 hexon trimer in complex with human coagulation factor X (FX)
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