Fibroblast growth factor: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Michal Harel (talk | contribs) No edit summary |
Michal Harel (talk | contribs) No edit summary |
||
| Line 5: | Line 5: | ||
'''Fibroblast growth factors''' (FGF) are involved in angiogenesis, wound-healing and embryonic development. FGF is heparin-binding protein. FGF require heparan sulfate (HS) to activate the four FGF cell-surface receptors (FGFR). In vertebrates there are 23 members in the FGF family<ref>PMID:11276432</ref>. <br /> | '''Fibroblast growth factors''' (FGF) are involved in angiogenesis, wound-healing and embryonic development. FGF is heparin-binding protein. FGF require heparan sulfate (HS) to activate the four FGF cell-surface receptors (FGFR). In vertebrates there are 23 members in the FGF family<ref>PMID:11276432</ref>. <br /> | ||
* '''FGF1''' is called acidic FGF.<br /> | * '''FGF1''' is called acidic FGF.<br /> | ||
* '''FGF2''' is called basic FGF. See also [[API5-FGF2]].<br /> | * '''FGF2''' is called basic FGF. See also [[API5-FGF2 complex]].<br /> | ||
* '''FGF4''' has multiple roles during vertebrate embryogenesis<ref>PMID:18792115</ref>.<br /> | * '''FGF4''' has multiple roles during vertebrate embryogenesis<ref>PMID:18792115</ref>.<br /> | ||
* '''FGF7''' is called '''keratinocyte growth factor''' which is present in the epitheliazation-phase of wound healing when keratinocytes are covering the wound<ref>PMID:11052999</ref>. FGF7 is aparacrine growth factor in the breast<ref>PMID:12697038</ref>. | * '''FGF7''' is called '''keratinocyte growth factor''' which is present in the epitheliazation-phase of wound healing when keratinocytes are covering the wound<ref>PMID:11052999</ref>. FGF7 is aparacrine growth factor in the breast<ref>PMID:12697038</ref>. | ||
