Protein DJ-1: Difference between revisions

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<StructureSection load='6afa' size='340' side='right' caption='Human DJ-1 complex with inhibitor isatin and Cl-1 (green) (PDB code [[6afa]]).' scene='86/864103/Cv/1'>
<StructureSection load='6afa' size='340' side='right' caption='Human DJ-1 complex with inhibitor isatin and Cl-1 (green) (PDB code [[6afa]]).' scene='86/864103/Cv/1'>
 
__TOC__
== Function ==
== Function ==


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The 3D structure of DJ-1 complex with the inhibitor isatin shows the covalent bond formed between isatin and DJ-1 <scene name='86/864103/Cv/4'>conserved residue C106</scene> as well as the <scene name='86/864103/Cv/5'>numerous H-bonding interactions</scene> between the inhibitor and the protein<ref>PMID:30063823</ref>. <scene name='86/864103/Cv/6'>Whole binding site</scene>. Water molecules are shown as red spheres.
The 3D structure of DJ-1 complex with the inhibitor isatin shows the covalent bond formed between isatin and DJ-1 <scene name='86/864103/Cv/4'>conserved residue C106</scene> as well as the <scene name='86/864103/Cv/5'>numerous H-bonding interactions</scene> between the inhibitor and the protein<ref>PMID:30063823</ref>. <scene name='86/864103/Cv/6'>Whole binding site</scene>. Water molecules are shown as red spheres.
 
== 3D structures of protein DJ-1 ==
[[Protein DJ-1 3D structures]]


</StructureSection>
</StructureSection>

Latest revision as of 08:40, 30 July 2026

Human DJ-1 complex with inhibitor isatin and Cl-1 (green) (PDB code 6afa).

Drag the structure with the mouse to rotate

References

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky