Protein kinase C 3D structures: Difference between revisions

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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|


*'''Conventional PKCs'''
*'''Conventional PKCs'''; Domains – C1 63-169; C2 155-293; kinase 322-673


*PKC-α
*PKC-α


**[[2eli]] – hCPKC-α C1 domain – human – NMR<br />
**[[2eli]] – hCPKC-α C1 domain – human – NMR<br />
**[[4dnl]] - hCPKC-α C2 domain<br />
**[[4dnl]], [[9c5f]] - hCPKC-α C2 domain<br />
**[[3iw4]], [[4ra4]] - hCPKC-α kinase domain + inhibitor<br />
**[[3iw4]], [[4ra4]] - hCPKC-α kinase domain + inhibitor<br />
**[[8u37]] - hCPKC- kinase domain + drug<br />
**[[8uak]] - hCPKC- kinase domain (mutant) + drug<br />
**[[1dsy]], [[3rdj]], [[3twy]], [[2nce]] – rCPKC-α C2 domain – rat
**[[1dsy]], [[3rdj]], [[3twy]], [[2nce]] – rCPKC-α C2 domain – rat


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*PKC-β
*PKC-β


**[[2i0e]] - hCPKC-β II catlytic domain + inhibitor<br />
**[[8se1]], [[8se2]], [[8se3]], [[8se4]] – hCPKC-beta <br />
**[[2i0e]] - hCPKC-β II catalytic domain 322-673 + inhibitor<br />
**[[9s9t]]  - hCPKC-beta catalytic domain (mutant) + drug<br />
**[[1a25]] – rCPKC-β C2 domain<br />  
**[[1a25]] – rCPKC-β C2 domain<br />  
**[[3pfq]] - rCPKC-β II (mutant)<br />
**[[3pfq]] - rCPKC-β II (mutant)<br />
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**[[3uey]], [[3uff]], [[3ugd]], [[3ugi]], [[3ugl]]  - mNPKC-δ C1B domain (mutant)<br />
**[[3uey]], [[3uff]], [[3ugd]], [[3ugi]], [[3ugl]]  - mNPKC-δ C1B domain (mutant)<br />
**[[6uwa]] - mNPKC-δ C2+C1B domains<br />
**[[6uwa]] - mNPKC-δ C2+C1B domains<br />
**[[9ecs]] - rNPKC-δ C1B domain + drug<br />
**[[1ptr]] - mNPKC-δ C2 domain + phorbol-acetate
**[[1ptr]] - mNPKC-δ C2 domain + phorbol-acetate


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**[[3zh8]] - hAPKC-ι kinase domain (mutant) + inhibitor<br />
**[[3zh8]] - hAPKC-ι kinase domain (mutant) + inhibitor<br />
**[[1wmh]] - hAPKC-ι PB1 domain + PAR6 alpha<br />
**[[1wmh]] - hAPKC-ι PB1 domain + PAR6 alpha<br />
**[[4dc2]], [[5li1]] - hAPKC-ι kinase domain + PAR3 peptide<br />
**[[4dc2]], [[5li1]], [[8r3x]] - hAPKC-ι kinase domain + PAR3 peptide<br />
**[[8r3y]], [[9ejk]], [[9ejl]], [[9ejm]] - hAPKC-ι kinase domain + LLGL + par-6 - Cryo EM<br />
**[[5lih]] - hAPKC-ι kinase domain + PKC-εζ peptide<br />
**[[5lih]] - hAPKC-ι kinase domain + PKC-εζ peptide<br />


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