3v5q | pdb_00003v5q

Discovery of a selective TRK Inhibitor with efficacy in rodent cancer tumor models

spinqualitylabelsall models 3v5q, resolution 2.20Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3v5q is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.2001Å Ligands: 0F4, CL Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function NTRK3_HUMAN Receptor for neurotrophin-3 (NT-3). This is a tyrosine-protein kinase receptor. Known substrates for the trk receptors are SHC1, PI-3 kinase, and PLCG1. The different isoforms do not have identical signaling properties. See Also TrkB tyrosine kinase receptor Tyrosine kinase receptor 3D structures

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