Gelsolin
Gelsolin (GLS) is a protein regulator of actin assembly and disassembly. The images at the top and at the right correspond to one representative gelsolin structure, i.e. the human gelsolin (3ffn), it has dimeric form. It contains 6 homologous domains S1 to S6.
3D Structures of GLS
GLS
3ffn – hGLS – human
2fgh – hoGLS+ATP – horse
1d0n - hoGLS
GLS domains S1-S3
3ffk – hGLS domains S1-S3+actin
1rgi - hoGLS domains S1-S3+actin
GLS domains S4-S6
1h1v - hGLS domains S4-S6+actin
1nph - GLS domains S4-S6+Ca – mouse
GLS domain S1
2ff3 - hGLS domain S1+N-WASP+actin
2ff6 - hGLS domain S1+Ciboulot domain 2+actin
1mdu - hGLS domain S1+chActin – chicken
1d4x - hGLS domain S1+CeActin+Mg-ATP – Caenorhabditis elegans
1esv - hGLS domain S1+rActin+latrunculin – rabbit
1eqy - hGLS domain S1+rActin
1yvn - hGLS domain S1+yActin (mutant) – yeast
1yag - hGLS domain S1+yActin
1kcq – hGLS domainS1+Cd
1c0f - hGLS domain S1+DdActin+Ca-ATP - Dictyostelium discoideum
1c0g, 1dej - hGLS domain S1+DdActin (mutant)
3ci5, 3cip, 1nlv – DdGLS domain S1+actin
1nm1 - DdGLS domain S1+actin+Mg-ATP
3cjb - rGLS domain S1+rActin
3cjc - rGLS domain S1+rActin+DNAse I
1nmd - hGLS domain S1+actin+Ca+ATP
GLS C-terminal
2fh1, 2fh2, 2fh3, 2fh4 – hGLS C-terminal
1p8x - hGLS C-terminal+Ca
1p8z – hGLS fraction+rActin
