2qo3 | pdb_00002qo3

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Template:STRUCTURE 2qo3

File:2qo3.png

Crystal Structure of [KS3][AT3] didomain from module 3 of 6-deoxyerthronolide B synthase

Template:ABSTRACT PUBMED 17719492

About this Structure

2qo3 is a 2 chain structure with sequence from Saccharopolyspora erythraea. Full crystallographic information is available from OCA.

Reference

  1. Tang Y, Chen AY, Kim CY, Cane DE, Khosla C. Structural and mechanistic analysis of protein interactions in module 3 of the 6-deoxyerythronolide B synthase. Chem Biol. 2007 Aug;14(8):931-43. PMID:17719492 doi:10.1016/j.chembiol.2007.07.012
  2. Chen AY, Cane DE, Khosla C. Structure-based dissociation of a type I polyketide synthase module. Chem Biol. 2007 Jul;14(7):784-92. PMID:17656315 doi:10.1016/j.chembiol.2007.05.015
  3. Tang Y, Kim CY, Mathews II, Cane DE, Khosla C. The 2.7-Angstrom crystal structure of a 194-kDa homodimeric fragment of the 6-deoxyerythronolide B synthase. Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11124-9. Epub 2006 Jul 14. PMID:16844787
  4. Kim CY, Alekseyev VY, Chen AY, Tang Y, Cane DE, Khosla C. Reconstituting modular activity from separated domains of 6-deoxyerythronolide B synthase. Biochemistry. 2004 Nov 9;43(44):13892-8. PMID:15518537 doi:10.1021/bi048418n

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