1ef3 | pdb_00001ef3

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Template:STRUCTURE 1ef3

File:1ef3.png

FIDARESTAT BOUND TO HUMAN ALDOSE REDUCTASE

Template:ABSTRACT PUBMED 10882376

About this Structure

1ef3 is a 2 chain structure of Aldose Reductase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  1. Oka M, Matsumoto Y, Sugiyama S, Tsuruta N, Matsushima M. A potent aldose reductase inhibitor, (2S,4S)-6-fluoro-2', 5'-dioxospiro[chroman-4,4'-imidazolidine]-2-carboxamide (Fidarestat): its absolute configuration and interactions with the aldose reductase by X-ray crystallography. J Med Chem. 2000 Jun 15;43(12):2479-83. PMID:10882376

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