3hqu | pdb_00003hqu
From Proteopedia
PHD2:Fe:UN9:partial HIF1-alpha substrate complex
Template:ABSTRACT PUBMED 19604478
About this Structure
3hqu is a 2 chain structure of Factor inhibiting HIF, Hypoxia-inducible factor prolyl hydroxylase and Prolyl hydroxylase domain with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Chowdhury R, McDonough MA, Mecinovic J, Loenarz C, Flashman E, Hewitson KS, Domene C, Schofield CJ. Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases. Structure. 2009 Jul 15;17(7):981-9. PMID:19604478 doi:S0969-2126(09)00224-X
- McDonough MA, Li V, Flashman E, Chowdhury R, Mohr C, Lienard BM, Zondlo J, Oldham NJ, Clifton IJ, Lewis J, McNeill LA, Kurzeja RJ, Hewitson KS, Yang E, Jordan S, Syed RS, Schofield CJ. Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2). Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9814-9. Epub 2006 Jun 16. PMID:16782814
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Chowdhury, R.
- McDonough, M A.
- Schofield, C J.
- Activator
- Congenital erythrocytosis
- Dioxygenase
- Disease mutation
- Dna-binding
- Double stranded beta-helix
- Hydroxylation
- Iron
- Isopeptide bond
- Metal-binding
- Nucleus
- Oxidoreductase
- Oxidoreductase-transcription complex
- Phosphoprotein
- S-nitrosylation
- Transcription
- Transcription regulation
- Vitamin c
- Zinc-finger
