2wc0 | pdb_00002wc0
From Proteopedia
CRYSTAL STRUCTURE OF HUMAN INSULIN DEGRADING ENZYME IN COMPLEX WITH IODINATED INSULIN
Template:ABSTRACT PUBMED 19321446
About this Structure
2wc0 is a 6 chain structure of Insulin-Degrading Enzyme and Molecular Playground/Insulin with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Manolopoulou M, Guo Q, Malito E, Schilling AB, Tang WJ. Molecular basis of catalytic chamber-assisted unfolding and cleavage of human insulin by human insulin-degrading enzyme. J Biol Chem. 2009 May 22;284(21):14177-88. Epub 2009 Mar 25. PMID:19321446 doi:10.1074/jbc.M900068200
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Homo sapiens
- Insulysin
- Guo, Q.
- Malito, E.
- Manolopoulou, M.
- Schilling, A B.
- Tang, W J.
- Carbohydrate metabolism
- Cleavage on pair of basic residue
- Dioxane
- Disulfide bond
- Glucose metabolism
- Hormone
- Human insulin-degrading enzyme
- Hydrolase
- Hydrolase-hormone complex
- Hydrolase/hormone
- Insulin
- Metal-binding
- Metalloprotease
- Protease
- Secreted
