3u2c | pdb_00003u2c
From Proteopedia
Aldose reductase in complex with NSAID-type inhibitor at 1.0 A resolution
Function
[ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.
About this Structure
3u2c is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Steuber H. An Old NSAID Revisited: Crystal Structure of Aldose Reductase in Complex with Sulindac at 1.0 A Supports a Novel Mechanism for its Anticancer and Antiproliferative Effects. ChemMedChem. 2011 Oct 13. doi: 10.1002/cmdc.201100374. PMID:21997888 doi:10.1002/cmdc.201100374
