3ajv | pdb_00003ajv
From Proteopedia
Splicing endonuclease from Aeropyrum pernix
Template:ABSTRACT PUBMED 21050862
Function
[ENDA_AERPE] Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp (By similarity).
About this Structure
3ajv is a 4 chain structure with sequence from Aerpe and Aerpx. Full crystallographic information is available from OCA.
See Also
Reference
- Okuda M, Shiba T, Inaoka DK, Kita K, Kurisu G, Mineki S, Harada S, Watanabe YI, Yoshinari S. A Conserved Lysine Residue in the Crenarchaea-Specific Loop is Important for the Crenarchaeal Splicing Endonuclease Activity. J Mol Biol. 2010 Nov 2. PMID:21050862 doi:10.1016/j.jmb.2010.10.050
