Atlastin

<StructureSection load='3q5e' size='340' side='right' caption='Structure of human atlastin cytoplasmic domain complex with GDP (PDB code 3q5e).' scene=>

Function

Atlastin (ATN) is a GTPase and a Golgi body transmembrane protein. ATN was shown to be required in membrane fusion and ER formation in Drosophila melanogaster.

Disease

Defects in the ATN gene are a cause of spastic paraplegia type 3.

3D structures of atlastin

Updated on 10-June-2014

3q5d, 3q5e, 3qnu, 3qof – hATN cytoplasmic domain + GDP – human
4idn – hATN cytoplasmic domain + GNP
4idp – hATN cytoplasmic domain (mutant) + GNP
4ido – hATN cytoplasmic domain + GDP + AlF4
4idq – hATN cytoplasmic domain (mutant) + GDP + AlF4

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky